691856-96-9

Basic information

• Product Name: methyl 2-(4-fluorophenyl)-5-hydroxy-1-benzofuran-3-carboxylate
• Synonyms: methyl 2-(4-fluorophenyl)-5-hydroxy-1-benzofuran-3-carboxylate
• CAS NO: 691856-96-9
• Molecular Weight: 286.259
• Mol File: 691856-96-9.mol

Chemical Properties

• CAS DataBase Reference: methyl 2-(4-fluorophenyl)-5-hydroxy-1-benzofuran-3-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2-(4-fluorophenyl)-5-hydroxy-1-benzofuran-3-carboxylate(691856-96-9)
• EPA Substance Registry System: methyl 2-(4-fluorophenyl)-5-hydroxy-1-benzofuran-3-carboxylate(691856-96-9)

Safety Data

• Hazardous Substances Data: 691856-96-9(Hazardous Substances Data)

Upstream product

• 63131-29-3 methyl 4-fluorobenzoyl acetate 
• 106-51-4 p-benzoquinone 

Downstream Products

• 1072843-89-0 methyl 5-(allyloxy)-2-(4-fluorophenyl)benzofuran-3-carboxylate 
• 1072844-14-4 2-(4-fluorophenyl)‐5‐hydroxybenzofuran‐3‐carboxylic acid 
• 1423007-42-4 5-cyclopropyl-6-[N-(3-fluoro-4-nitrophenyl)methanesulfonamido]-2-(4-fluorophenyl)-N-methyl-1-benzofuran-3-carboxamide 
• 1423007-43-5 6-[N-(4-amino-3-fluorophenyl)methanesulfonamido]-5-cyclopropyl-2-(4-fluorophenyl)-N-methyl-1-benzofuran-3-carboxamide 
• 1423007-44-6 6-[N-(4-bromo-3-fluorophenyl)methanesulfonamido]-5-cyclopropyl-2-(4-fluorophenyl)-N-methyl-1-benzofuran-3-carboxamide 
• 1423007-45-7 5-cyclopropyl-6-(N-(3-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methylsulfonamido)-2-(4-fluorophenyl)-N-methylbenzofuran-3-carboxamide 
• 1423007-41-3 (4-{N-[5-cyclopropyl-2-(4-fluorophenyl)-3-(methylcarbamoyl)-1-benzofuran-6-yl]methanesulfonamido}-2-fluorophenyl)boronic acid 
• 1423007-47-9 5-cyclopropyl-6-[N-(3-fluoro-4-nitrophenyl)methanesulfonamido]-2-(4-fluorophenyl)-N-methyl-1-benzofuran-3-carboxamide 
• 1423007-48-0 6-[N-(4-amino-2-fluorophenyl)methanesulfonamido]-5-cyclopropyl-2-(4-fluorophenyl)-N-methyl-1-benzofuran-3-carboxamide 
• 1423007-49-1 6-[N-(4-bromo-2-fluorophenyl)methanesulfonamido]-5-cyclopropyl-2-(4-fluorophenyl)-N-methyl-1-benzofuran-3-carboxamide 
• 1423007-50-4 5-cyclopropyl-6-(N-(2-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methylsulfonamido)-2-(4-fluorophenyl)-N-methylbenzofuran-3-carboxamide 
• 1423007-46-8 (4-{N-[5-cyclopropyl-2-(4-fluorophenyl)-3-(methylcarbamoyl)-1-benzofuran-6-yl]methanesulfonamido}-3-fluorophenyl)boronic acid 
• 1423007-38-8 (3-{N-[2-(4-fluorophenyl)-5-cyclopropyl-3-(methylcarbamoyl)-1-benzofuran-6-yl]methanesulfonamido}phenyl)boronic acid 
• 1423007-40-2 5-cyclopropyl-2-(4-fluorophenyl)-N-methyl-6-(N-(3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methylsulfonamido)benzofuran-3-carboxamide 

Relevant articles and documents

THERAPEUTIC METHODS

The present invention features a method for the treatment of Hepatitis C in a human in need thereof comprising administering a compound of Formulas (II) or (IIB) described herein or a pharmaceutically acceptable salt thereof in combination with one or more alternative Hepatitis C therapeutic agents

BENZOFURAN COMPOUNDS FOR THE TREATMENT OF HEPATITIS C VIRUS INFECTIONS

The present invention features compounds of formula (I) and salts thereof, pharmaceutical compositions comprising said compounds, and uses of such compounds in treating or preventing viral infections, such as HCV infections, and diseases associated with such infections.

BENZOFURAN- CARBOXAMIDE DERIVATIVES AS ANTIVIRAL AGENTS

A compound of the formula (I): as defined herein, or a pharmaceutically acceptable salt thereof, or a pharmaceutical composition containing a compound of the formula (I) for use in inhibiting hepatitis C virus polymerase and/or of treating or preventing an illness due to hepatitis C virus,