691863-36-2

Upstream product

• 691863-12-4 methanesulfonic acid 3-[1-(3-fluoro-4-morpholin-4-yl-phenyl)-1H-pyrrol-3-yl]-2-oxo-oxazolidin-5-ylmethyl ester 
• 691862-88-1 [1-(3-fluoro-4-morpholin-4-yl-phenyl)-1H-pyrrol-3-yl]-carbamic acid benzyl ester 
• 691863-00-0 3-[1-(3-fluoro-4-morpholin-4-yl-phenyl)-1H-pyrrol-3-yl]-5-hydroxymethyl-oxazolidin-2-one 
• 691862-77-8 1-(3-fluoro-4-morpholin-4-yl-phenyl)-1H-pyrrole-3-carboxylic acid 
• 691862-67-6 1-(3-fluoro-4-morpholin-4-yl-phenyl)-1H-pyrrole-3-carbaldehyde 
• 93246-53-8 3-fluoro-4-(morpholinyl)aniline 
• 691863-24-8 5-azidomethyl-3-[1-(3-fluoro-4-morpholin-4-yl-phenyl)-1H-pyrrol-3-yl]-oxazolidin-2-one 

Relevant academic research and scientific papers

Synthesis and in vitro antimycobacterial activity of novel 3-(1H-pyrrol-1-yl)-2-oxazolidinone analogues of PNU-100480

Pursuing our search program for new antitubercular drugs we decided to explore the potentiality of oxazolidinone moiety by synthesizing novel 3-(1H-pyrrol-1-yl)-2-oxazolidinone analogues of PNU-100480. The new derivatives were tested against atypical mycobacteria as well as against drug resistant Mycobacterium tuberculosis and some of them exhibited a fairly good activity against Mycobacterium avium complex (MAC).