691875-29-3

Upstream product

• 691876-76-3 C₂₉H₂₈F₆N₄OS 
• 624-83-9 methyl isocyanate 
• 691876-75-2 C₃₄H₃₆F₆N₄O₃S 
• 86978-09-8 tert-butyl (2E)-2-[(tert-butoxycarbonyl)inimo]-4-(2-ethoxy-2-oxoethyl)-1,3-thiazole-3-(2H)-carboxylate 
• 139354-84-0 ethyl 2-(2-tert-butoxycarbonylaminothiazol-4-yl)-4-pentenoate 
• 139354-85-1 ethyl 2-(2-tert-butoxycarbonylaminothiazol-4-yl)-3-formylpropanoate 
• 691876-47-8 C₂₇H₃₅N₃O₄S 
• 691876-48-9 C₂₅H₃₁N₃O₄S 

Relevant academic research and scientific papers

α-Aminothiazole-γ-aminobutanoic amides as potent, small molecule CCR2 receptor antagonists

A series of racemic and homochiral α-aminothiazole-γ-aminobutyroamides that display high affinities for human and murine CCR2 and functional antagonism by inhibition of monocyte recruitment are described. A representative example is (2S)-2-[2-(acetylamino

GAMMA-AMINOAMIDE MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY

The present invention is directed to compounds of the formula (I), wherein R1, R2, R3, R4, R5, R6, R7, R8, R11, R12, W, X, and n are defined herein, which are useful as modulators of chemokine receptor activity. In particular, these compounds are useful as modulators of the chemokine receptor CCR-2.