691875-81-7

Usage

Uses

Used in Pharmaceutical Industry:
4-(2-Fluorophenyl) piperidine hydrochloride is used as a pharmaceutical intermediate for the synthesis of various drugs and medications. Its unique chemical structure and properties make it a valuable component in the development of new therapeutic agents.
Used in Medicinal Chemistry Research:
4-(2-FLUOROPHENYL) PIPERIDINE HYDROCHLORIDE is utilized in medicinal chemistry research to explore its potential pharmacological properties and evaluate its efficacy in treating different medical conditions. The hydrochloride salt form of 4-(2-Fluorophenyl) piperidine enhances its solubility and stability, facilitating its incorporation into pharmaceutical formulations and improving its therapeutic potential.
Used in Drug Development:
4-(2-Fluorophenyl) piperidine hydrochloride is employed in drug development as a key building block for the creation of novel therapeutic agents. Its unique structure and properties allow for the design of drugs with specific target interactions, potentially leading to more effective treatments for various diseases and conditions.
Used in Solubility and Stability Enhancement:
In pharmaceutical formulations, 4-(2-Fluorophenyl) piperidine hydrochloride is used to improve the solubility and stability of other active pharmaceutical ingredients. Its hydrochloride salt form provides a stable and soluble platform for the development of effective drug delivery systems, ensuring optimal bioavailability and therapeutic efficacy.

InChI:InChI=1S/C11H14FN.ClH/c12-11-3-1-9(2-4-11)10-5-7-13-8-6-10;/h1-4,10,13H,5-8H2;1H

Upstream product

• 79099-07-3 N-tert-butyloxycarbonylpiperidin-4-one 
• 138647-49-1 4-Trifluoromethanesulfonyloxy-3,6-dihydro-2H-pyridine-1-carboxylic acid tert-butyl ester 

Downstream Products

• 1034592-78-3 {1-(2-chloro-phenyl)-5-(4-chloro-phenyl)-3-[4-(2-fluoro-phenyl)-piperidine-1-carbonyl]-1H-pyrazol-4-yl}-acetic acid ethyl ester 
• 1276655-75-4 2-((4-(2-fluorophenyl)piperidin-1-yl)methyl)-1-methyl-1H-benzo-[d]imidazole hydrochloride 
• 1313600-44-0 {3-(4-chloro-phenyl)-2-(2-chloro-phenyl)-5-[4-(2-fluoro-phenyl)-piperidine-1-carbonyl]-3H-imidazol-4-yl}-acetonitrile 
• 1175689-62-9 2-fluoro-6-[4-(2-fluoro-phenyl)-piperidine-1-sulfonyl]pyridine 
• 1121052-71-8 (3-chloro-6-furan-3-yl-8-trifluoromethyl-imidazo[1,2-a]pyridine-2-yl)-[4-(2-fluoro-phenyl)-piperidin-1-yl]-methanone 

Relevant academic research and scientific papers

Saturated Nitrogen and N-Acylated Heterocycles Potentiating the Activity of an Active Antibiotic against Mycobacteria

The present invention concerns a compound of general formula (I): in which n=0 or 1, R1 represents an optionally substituted alkyl chain, in particular substituted alkyl chain, in particular substituted with fluorine, X is chosen from N and CH, and R2 is

AZABENZIMIDAZOLYL COMPOUNDS

Compounds and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula (I), as defined in the specification. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.

BENZIMIDAZOLYL COMPOUNDS AS POTENTIATORS OF MGLUR2 SUBTYPE OF GLUTAMATE RECEPTOR

Compounds and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula (I) as defined in the specification. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.

GAMMA-AMINOAMIDE MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY

The present invention is directed to compounds of the formula (I), wherein R1, R2, R3, R4, R5, R6, R7, R8, R11, R12, W, X, and n are defined herein, which are useful as modulators of chemokine receptor activity. In particular, these compounds are useful as modulators of the chemokine receptor CCR-2.