69250-03-9

Upstream product

• 61271-32-7 3-formyl-2-phenyl-2,4,5,6-tetrahydro-1,4,6,6-tetramethylcyclopentapyrrole-4-carbonitrile 
• 61271-31-6 1,3-bis(chloromethyl)-2,4,5,6-tetrahydro-4,6,6-trimethyl-2-phenylcyclopentapyrrole-4-carbonitrile 
• 54609-27-7 1,3,4,6,6-pentamethyl-2-phenyl-2,4,5,6-tetrahydro-cyclopenta[c]pyrrole-4-carbonitrile 

Downstream Products

• 69250-41-5 2-Phenyl-2,4,5,6-tetrahydro-1-hydroxymethyl-3,4,6,6-tetramethylcyclopenta[c]pyrrole-4-carboxamide 

Relevant academic research and scientific papers

Experimental anti-ulcer drugs. IV 1,3-Disubstituted 2,4,5,6-tetrahydro-4,6,6-trimethyl-2-phenylcyclopenta[c]pyrrole-4-carboxamides

The synthesis of 1,3-disubstituted 2,4,5,6-tetrahydro-4,6,6-trimethyl-2-phenylcyclopenta[c]pyrrole-4-carboxamides is reported. The derivatives included R1 = R3 = H, R1 = CH2OH with R3 = H (16)(C1

Cyclopenta[c]pyrrole derivatives

2,4,5,6-Tetrahydrocyclopenta[c]pyrrole-4-carboxamide and 4-thiocarboxamide derivatives useful as anti-secretory and anti-ulcer agents are prepared by hydrolysis or thiohydrolysis of the corresponding 2,4,5,6-tetrahydrocyclopenta[c]pyrrole-4-carbonitriles or, in the case of the thiocarboxamides, by reaction of the 4-carboxamide with phosphorus pentasulfide.