69265-58-3Relevant academic research and scientific papers
Anomalous N-methylmorpholine Af-oxide/osmium tetroxide oxidation of penicillins and cephalosporins
Tama, Laeszloe,Szoeke, Gabriella N.,Gunda, Tamaes E.,Sziaricskai, Ferenc
, p. 207 - 212 (2007/10/03)
The penicillin and cephalosporin sulfides and β-sulfoxides behave suprisingly disparately when subjected to oxidation with N-methylmorpholine W-oxide and osmium tetroxide: while penicillins are inert to this oxidation procedure, their sulfoxides are clean
A very mild and quantitative oxidation of cephalosporins with dimethyldioxirane
Gunda, Tamas E.,Tamas, Laszlo,Salyi, Szabolcs,Nemes, Csaba,Sztaricskai, Ferenc
, p. 7111 - 7114 (2007/10/02)
The cephalosporins 1-3 and Δ2-cephem 4 were oxidized in quantative yields to their sulfones with dimethyldioxirane. While in the case of 2-methylene-cephems (5,6) the exocyclic double bond oxidized simultaneously to the corresponding epoxide, t
