69267-59-0 Usage
Uses
Used in Pharmaceutical Industry:
2-(4-aminophenyl)-1,2-dihydro-1,5-dimethyl-3H-pyrazol-3-one is used as a building block for the synthesis of other pharmaceutical and biologically active compounds due to its potential biological and pharmacological activities.
Used in Medicinal Chemistry Research:
2-(4-aminophenyl)-1,2-dihydro-1,5-dimethyl-3H-pyrazol-3-one is used as an important target for research in the field of medicinal chemistry, given its anti-inflammatory, analgesic, and antipyretic effects.
Check Digit Verification of cas no
The CAS Registry Mumber 69267-59-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,9,2,6 and 7 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 69267-59:
(7*6)+(6*9)+(5*2)+(4*6)+(3*7)+(2*5)+(1*9)=170
170 % 10 = 0
So 69267-59-0 is a valid CAS Registry Number.
InChI:InChI=1/C11H13N3O/c1-8-7-11(15)14(13(8)2)10-5-3-9(12)4-6-10/h3-7H,12H2,1-2H3
69267-59-0Relevant academic research and scientific papers
Pyrazolone methylamino piperidine derivatives as novel CCR3 antagonists
Pegurier, Cecile,Collart, Philippe,Danhaive, Pierre,Defays, Sabine,Gillard, Michel,Gilson, Frederic,Kogej, Thierry,Pasau, Patrick,Van Houtvin, Nathalie,Van Thuyne, Marc,van Keulen, BerendJan
, p. 4228 - 4231 (2008/02/09)
The discovery and optimization of a novel class of potent CCR3 antagonists is described. Details of synthesis and SAR are given together with some ADME properties of selected compounds. An optimal balance between activities, physicochemical properties, and in vitro metabolic stability was reached by the proper choice of substituents.
