69271-42-7Relevant academic research and scientific papers
A facile and simple synthesis of novel 2-(substituted)-5-(1-methyl-1H- indazol-3-yl)-oxazole derivatives
Reddy, E. Vishnu Vardhan,Ramanatham,Devanna,Srinivasa Reddy,Rajender
, p. E221-E227 (2013/06/05)
Novel 2-(substituted)-5-(1-methyl-1H-indazol-3-yl)-oxazoles (13) were synthesized in moderate yields, from 1-methyl-1H-Indazole 3-carboxylic acid (1), by converting it into a variety of amides (12) and further its heterocyclization. The structures of all the compounds have been elucidated on the basis of IR, 1H-NMR, and HRMS.
Discovery and pharmacological profile of new 1H-indazole-3-carboxamide and 2H-pyrrolo[3,4-c]quinoline derivatives as selective serotonin 4 receptor ligands
Furlotti, Guido,Alisi, Maria Alessandra,Apicella, Claudia,Capezzone De Joannon, Alessandra,Cazzolla, Nicola,Costi, Roberta,Cuzzucoli Crucitti, Giuliana,Garrone, Beatrice,Iacovo, Alberto,Magarò, Gabriele,Mangano, Giorgina,Miele, Gaetano,Ombrato, Rosella,Pescatori, Luca,Polenzani, Lorenzo,Rosi, Federica,Vitiello, Marco,Di Santo, Roberto
, p. 9446 - 9466 (2013/01/16)
Since the discovery of the serotonin 4 receptor (5-HT4R), a large number of receptor ligands have been studied. The safety concerns and the lack of market success of these ligands have mainly been attributed to their lack of selectivity. In thi
Indole and indazole derivatives, for the treatment and prophylaxis of cerebral disorders, their preparation and their use
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, (2008/06/13)
Compounds of formula (I) : [in which R1 and R2 are each hydrogen or various organic groups, pis 0, 1, 2 or 3, U is -CO- or -CH(OR3)- where R3 is hydrogen or a hydroxy-protecting group, V is an optionally unsaturated aliphatic hydrocarbon group and W is a nitrogen-containing group] are useful in the treatment and prophylaxis of dementia especially of the Alzheimer's type.
