69274-98-2Relevant academic research and scientific papers
Total synthesis of the cytotoxic guaipyridine sesquiterpene alkaloid (+)-cananodine
Craig, Donald,Henry, Gavin D.
, p. 3558 - 3561 (2007/10/03)
The enantiospecific total synthesis of the cytotoxic guaipyridine sesquiterpene alkaloid (+)-cananodine (1) is described. A chiral pool/chiral auxiliary based approach is described for the synthesis of a key oxazolidinone intermediate. Subsequent key step
SYNTHESIS OF NATURALLY OCCURRING (R)-(+)-MUSCOPYRIDINE
Utimoto, Kiitiro,Kato, Sadao,Tanaka, Michio,Hoshino, Yukihisa,Fujikura, Sadao,Nozaki, Hitosi
, p. 149 - 152 (2007/10/02)
Incorporation of the chiral center of (R)-4-methyl-5-hexenyl tosylate gives the title compound.The synthesis establishes the absolute configuration of the natural product.The title compound is also obtained from (Z)-1,2-dehydromuscopyridine by asymmetric reduction with chiral alkylboranes.
