69298-63-1Relevant academic research and scientific papers
Enyne Amides to Fused Pyridones: Scope and Limitations
Labadie, Sharada S.,Thai, Karine,Grandner, Jessica M.,Liu, Yanzhou,Parr, Brendan T.
, p. 14177 - 14191 (2021/08/24)
Herein we present an investigation into the scope and mechanism for the synthesis of cyclopentyl and heterocyclic fused pyridones from the corresponding enyne amides. In the presence of a secondary amine, cyclization proceeds smoothly to form 5,6-bicyclic
Synthesis of (+/-)-Actinidine by an Intramolecular Cycloaddition Process
Davies, Lyn B.,Greenberg, Sydney G.,Sammes, Peter G.
, p. 1909 - 1912 (2007/10/02)
A new synthesis of (+/-)-actinidine (1), which relies on intramolecular cycloaddition of an acetylene across a pyrimidine ring, is described.Preparation of 5-(hept-5-yn-2-yl)-4,6-dihydroxypyrimidine (2) followed by thermolysis afforded 1-hydroxyactinidine
