69304-83-2

Basic information

• Product Name: 2-amino-4-[[5-chloro-6-methyl-2-(methylsulphonyl)-4-pyrimidinyl]amino]benzenesulphonic acid
• Synonyms: 2-amino-4-[[5-chloro-6-methyl-2-(methylsulphonyl)-4-pyrimidinyl]amino]benzenesulphonic acid;2-Amino-4-[[5-chloro-6-methyl-2-(methylsulfonyl)-4-pyrimidinyl]amino]benzenesulfonic acid
• CAS NO: 69304-83-2
• Molecular Formula: C12H13ClN4O5S2
• Molecular Weight: 392.83842
• EINECS: 273-962-4
• Mol File: 69304-83-2.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Density: 1.657g/cm³
• Refractive Index: 1.66
• CAS DataBase Reference: 2-amino-4-[[5-chloro-6-methyl-2-(methylsulphonyl)-4-pyrimidinyl]amino]benzenesulphonic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-amino-4-[[5-chloro-6-methyl-2-(methylsulphonyl)-4-pyrimidinyl]amino]benzenesulphonic acid(69304-83-2)
• EPA Substance Registry System: 2-amino-4-[[5-chloro-6-methyl-2-(methylsulphonyl)-4-pyrimidinyl]amino]benzenesulphonic acid(69304-83-2)

Safety Data

• Hazardous Substances Data: 69304-83-2(Hazardous Substances Data)

Usage

Function

It is a sulphonamide-based drug used as a diuretic and antihypertensive agent.

Mechanism of Action

Inhibits the reabsorption of sodium and chloride ions in the kidneys.

Common Uses

Treatment of edema, hypertension, and congestive heart failure.

Target

Blocks the action of carbonic anhydrase, an enzyme involved in the reabsorption of sodium bicarbonate and water in the renal tubules.

Mode of Action

Binds effectively to the enzyme, inhibiting its activity.

Effect

Increases excretion of sodium, chloride, and water, thereby reducing fluid retention and lowering blood pressure.

InChI:InChI=1/C12H13ClN4O5S2/c1-6-10(13)11(17-12(15-6)23(2,18)19)16-7-3-4-9(8(14)5-7)24(20,21)22/h3-5H,14H2,1-2H3,(H,15,16,17)(H,20,21,22)