69314-60-9Relevant academic research and scientific papers
The first asymmetric Sonogashira coupling for the enantioselective generation of planar chirality in paracyclophanes
Kanda, Kazumasa,Koike, Tamami,Endo, Kohei,Shibata, Takanori
supporting information; experimental part, p. 1870 - 1872 (2009/10/17)
The double Sonogashira coupling of diiodoparacyclophanes with alkynes proceeded to give planarly chiral dialkynylparacyclophanes; a chiral Pd catalyst, which was prepared in situ from PdCl2(CH 3CN)2 and Taniaphos, realized the first asymmetric Sonogashira coupling with up to ca. 80% ee.
Quaternary ammonium compounds having muscle relaxation activity
-
, (2008/06/13)
A quaternary ammonium having a muscle relaxation activity compound represented by the formula (I): STR1 wherein R1 represents a methylene, a lower alkylenoxy, a lower alkenylene, a lower alkynylene, --CO--, --COO--, a lower alkylene carbonyloxy, --CH(OR5)--, a lower alkylenecarbonyl, a hydroxy lower alkylene, --O--, --S--, --SO--, or --SO2 --; R2 represents a hydrogen atom, a hydroxy lower alkyl, an aldehyde, a lower alkyl carbonyl, --NO2, or --NHR6 ; R3 represents a hydrogen atom of a group --R1 --(CH2)a --[CH(CH2 A)--CH2 ]b --A; R4 represents an anion; R5 and R6 represent a hydrogen atom or a acetyl; A represents a quaternary ammonium group; a represents an integer of 1 to 8; b represents 0 or 1; m represents an integer of 1 to 4; and (Z) represents a trivalent benzene ring, a trivalent naphthalene ring, a trivalent diphenyl or a trivalent ethane radical.
