693263-06-8

Upstream product

• 35323-09-2 (2-iodo-4,5-dimethoxyphenyl)acetic acid 
• 693263-05-7 4-formyl-6,7-methylenedioxyquinoline 
• 51048-62-5 4-methyl-6,7-methylenedioxyquinoline 
• 14268-66-7 benzo[1,3]dioxolo-5-ylamine 

Downstream Products

• 693263-07-9 3-(6,7-methylenedioxyquinolin-4-yl)-2-(2-iodo-4,5-dimethoxyphenyl)acrylic acid ethyl ester 
• 872036-79-8 3-(6,7-methylenedioxyquinolin-4-yl)-2-(2-iodo-4,5-dimethoxyphenyl)acrylic acid 2-(N,N-dimethylamino)propylamide 
• 872036-77-6 3-(6,7-methylenedioxyquinolin-4-yl)-2-(2-iodo-4,5-dimethoxyphenyl)acrylic acid 2-(N,N-dimethylamino)ethylamide 
• 872036-80-1 3-(6,7-methylenedioxyquinolin-4-yl)-2-(2-iodo-4,5-dimethoxyphenyl)acrylic acid N-methyl-N-[2-(dimethylamino)ethyl]amide 
• 872036-78-7 3-(6,7-methylenedioxyquinolin-4-yl)-2-(2-iodo-4,5-dimethoxyphenyl)acrylic acid 2-(N,N-dimethylamino)-1-methylethylamide 

Relevant academic research and scientific papers

Esters and amides of 2,3-dimethoxy-8,9-methylenedioxy-benzo[i] phenanthridine-12-carboxylic acid: Potent cytotoxic and topoisomerase I-targeting agents

The exceptional topoisomerase I-targeting activity and antitumor activity of 5-(2-N,N-dimethylamino)ethyl-8,9-dimethoxy-2,3-methylenedioxy-5H-dibenzo[c,h] [1,6]naphthyridin-6-one (ARC-111, topovale) prompted studies on similarly substituted benzo[i]phenan