693285-67-5

Basic information

• Product Name: [5-(1-METHYLETHYL)-1H-INDAZOL-4-YL] BORONIC ACID
• Synonyms: [5-(1-METHYLETHYL)-1H-INDAZOL-4-YL] BORONIC ACID
• CAS NO: 693285-67-5
• Molecular Formula: C10H13BN2O2
• Molecular Weight: 204.03
• Mol File: 693285-67-5.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: [5-(1-METHYLETHYL)-1H-INDAZOL-4-YL] BORONIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: [5-(1-METHYLETHYL)-1H-INDAZOL-4-YL] BORONIC ACID(693285-67-5)
• EPA Substance Registry System: [5-(1-METHYLETHYL)-1H-INDAZOL-4-YL] BORONIC ACID(693285-67-5)

Safety Data

• Hazardous Substances Data: 693285-67-5(Hazardous Substances Data)

Usage

General Description

[5-(1-methylethyl)-1H-indazol-4-yl] boronic acid is a chemical compound with the molecular formula C11H14BNO2. It is a boronic acid derivative that contains an indazole ring with a 1-methylethyl group attached at the 5-position. Boronic acids are widely used in organic synthesis and medicinal chemistry due to their ability to form stable complexes with diol-containing molecules. This specific compound may have applications in the development of pharmaceuticals, agrochemicals, and materials science due to its potential reactivity and ability to complex with specific biological targets. Further research and investigations are needed to explore its full range of applications and potential uses in various fields.

Upstream product

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• 610796-21-9 4-bromo-5-isopropyl-1H-indazole 

Relevant articles and documents

3-ARYL-5,6-DISUBSTITUTED PYRIDAZINES

The present invention provides compounds of Formula (I) or (II) salt form or prodrug thereof, wherein variables are defined herein, that are modulators of metalloproteases such as matrix metalloproteases (MMPs) and ADAMs. The compounds or compositions described herein can be used to treat diseases associated with metalloprotease activity including, for example, arthritis, cancer, cardiovascular disorders, skin disorders, inflammation or allergic conditions.

4,5-DISUBSTITUTED-2-ARYL PYRIMIDINES

4,5-disubstituted-2-arylpyrimidines of Formula (I) and Formula (II) are provided: wherein R1, R2, R3, R8, R9, A and Ar are defined herein. Such compounds are ligands of C5a receptors. Preferred compounds of Formula I and II bind to C5a receptors with high affinity and exhibit neutral antagonist or inverse activity at C5a receptors. The present invention also relates to pharmaceutical compositions comprising such compounds, and to the use of such compounds in treating a variety of inflammatory, cardiovascular, and immune system disorders. In addition, the present invention provides labeled 4,5-disubstituted-2-arylpyrimidines, which are useful as probes for the localization of C5a receptors.