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(Rp)-2'-deoxyadenosine cyclic 3',5'-phosphoranilidate is a chemical compound with the molecular formula C10H12N5O3P. It is a derivative of 2'-deoxyadenosine, a nucleoside that is a component of DNA. The compound features a cyclic phosphoramidate linkage between the 3' and 5' positions of the sugar moiety, which is a modification that can affect its interactions with enzymes and other biomolecules. This specific stereochemistry (Rp) indicates the configuration of the chiral center at the phosphorus atom. Such compounds are of interest in medicinal chemistry and nucleic acid research, as they can potentially be used to study or modulate the activity of enzymes that interact with DNA, or as potential therapeutic agents.

69330-95-6

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69330-95-6 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 69330-95-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,9,3,3 and 0 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 69330-95:
(7*6)+(6*9)+(5*3)+(4*3)+(3*0)+(2*9)+(1*5)=146
146 % 10 = 6
So 69330-95-6 is a valid CAS Registry Number.

69330-95-6Downstream Products

69330-95-6Relevant academic research and scientific papers

Ribonucleoside Cyclic 3',5'-Phosphoramidates: Synthesis, Stereochemistry, and Conversion into Ribonucleoside Cyclic 3',5'-Phosphorothioates and -Phosphates

Baraniak, Janina,Stec, Wojcieh J.

, p. 1645 - 1656 (2007/10/02)

Base- and O2'-protected nucleoside cyclic 3',5'-phosphates (1) react with aniline in the presence of triphenylphosphine-carbon tetrachloride to give the nucleoside cyclic 3',5'-phosphoramidates (2), which after separation into individual diaste

2'-DEOXYRIBONUCLEOSIDE 3'-ARYL PHOSPHORANILIDATES KEY INTERMEDIATES IN THE STEREOSPECIFIC SYNTHESIS OF 2'-DEOXYRIBONUCLEOSIDE CYCLIC 3',5'-PHOSPHOROTHIOATES AND DINUCLEOSIDE(3'->5')-PHOSPHOROTHIOATES

Lesnikowski, Z. J.,Niewiarowski, W.,Zielinski, W. S.,Stec, W. J.

, p. 15 - 32 (2007/10/02)

Phosphorylation of the 5'-O-monomethoxytrityl-2'-deoxyribonucleosides by means of aryl phosphoranilidochloridates gives the diastereomers of 5'-O-monomethoxytrityl-2'-deoxyribonucleoside 3'-aryl phosphoranilidates.Their separation can be performed by mean

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