69340-97-2

Basic information

• Product Name: 5-AMINO-4,6-DIHYDROXYPYRIMIDINE
• Synonyms: 5-AMINO-4,6-DIHYDROXYPYRIMIDINE;4(1H)-Pyrimidinone, 5-amino-6-hydroxy- (9CI);4,6-DIHYDROXY-5-AMINOPYRIMIDINE;5-AMINO-4,6-DIHYDROXYPYRIMIDINE 97%;5-amino-4-hydroxy-1H-pyrimidin-6-one;5-azanyl-4-hydroxy-1H-pyrimidin-6-one;5-AMinopyriMidine-4,6-diol;5-aMinopyriMidine-4,6-diol hydrochloride
• CAS NO: 69340-97-2
• Molecular Formula: C4H5N3O2
• Molecular Weight: 127.1
• Product Categories: PYRIMIDINE
• Mol File: 69340-97-2.mol
• Article Data: 2

Chemical Properties

• Melting Point: >300 °C
• Boiling Point: 387 °C at 760 mmHg
• Flash Point: 187.8 °C
• Appearance: /
• Density: 1.84 g/cm³
• Vapor Pressure: 1.53E-06mmHg at 25°C
• Refractive Index: 1.752
• PKA: 6.77±0.10(Predicted)
• CAS DataBase Reference: 5-AMINO-4,6-DIHYDROXYPYRIMIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-AMINO-4,6-DIHYDROXYPYRIMIDINE(69340-97-2)
• EPA Substance Registry System: 5-AMINO-4,6-DIHYDROXYPYRIMIDINE(69340-97-2)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 69340-97-2(Hazardous Substances Data)

Usage

Description

5-Amino-4,6-dihydroxypyrimidine is an organic compound characterized by the presence of an amino group attached to a pyrimidine ring, which features two hydroxyl groups at the 4th and 6th positions. 5-AMINO-4,6-DIHYDROXYPYRIMIDINE is known for its potential applications in various fields, particularly in the synthesis of complex organic molecules with antimicrobial properties.

Uses

Used in Pharmaceutical Research:
5-Amino-4,6-dihydroxypyrimidine serves as a valuable research reagent in the development of complex benzoxazinophenothiazines derivatives. These derivatives exhibit antimicrobial properties, making them promising candidates for the creation of new drugs to combat various microbial infections.
Used in Organic Synthesis:
In the field of organic synthesis, 5-Amino-4,6-dihydroxypyrimidine is utilized as a key intermediate for the synthesis of a wide range of organic compounds. Its unique structure allows for various chemical reactions, enabling the formation of diverse molecular structures with potential applications in different industries.
Used in Antimicrobial Applications:
5-Amino-4,6-dihydroxypyrimidine is used as a precursor in the synthesis of benzoxazinophenothiazines derivatives, which possess antimicrobial properties. These derivatives are being studied for their potential use in treating infections caused by various microorganisms, including bacteria and fungi.

InChI:InChI=1/C4H5N3O2/c5-2-3(8)6-1-7-4(2)9/h1H,5H2,(H2,6,7,8,9)

Upstream product

• 1549834-94-7 N-(4,6-dihydroxypyrimidin-5-yl)acetamide 

Downstream Products

• 33360-18-8 2-phenyloxazolo[5,4-d]pyrimidin-7-ol 
• 5413-85-4 5-amino-4,6-dichloropyridimine 
• 27433-55-2 2-methyloxazolo[5,4-d]pyrimidin-7-ol 

Relevant articles and documents

PROCESS FOR THE PREPARATION OF AN INTERMEDIATE FOR A TRIAZOLOPYRIMIDINE CARBONUCLEOSIDE

A process for the preparation of 4,6-dihalopyrimidin-5-amines of formula (II), or salts thereof, which comprises reacting 5-aminopyrimidin-4,6-diols of formula (III), or salts thereof, or a solvate either of the compound of formula (III) or of a salt thereof, with a halogenating agent, new intermediates useful in the preparation of the compound of formula (II) and processes for the preparation of these intermediates. The invention also refers to a process for the preparation of ticagrelor or a pharmaceutically acceptable salt thereof from 4,6-dihalo-2-(propylthio)pyrimidin-5-amine of formula (IIA).