693775-76-7Relevant academic research and scientific papers
Discovery of Diarylacrylonitriles as a Novel Series of Small Molecule Sortase A Inhibitors
Oh, Ki-Bong,Kim, Soo-Hwan,Lee, Jaekwang,Cho, Won-Jea,Lee, Taeho,Kim, Sanghee
, p. 2418 - 2421 (2004)
On the basis of a hit from random screening, a novel class of small-molecule sortase A inhibitors was generated. The primary structure-activity relationship and the minimal structural requirements for potency were established through structural modifications and molecular modeling studies.
