6941-20-4

Basic information

• Product Name: N-cyclohexyl-P,P-diphenylphosphinic amide
• Synonyms: N-Cyclohexyl-P,P-diphenylphosphinic amide; Phosphinic amide, N-cyclohexyl-P,P-diphenyl-
• CAS NO: 6941-20-4
• Molecular Formula: C₁₈H₂₂NOP
• Molecular Weight: 299.3471
• Mol File: 6941-20-4.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 434.2°C at 760 mmHg
• Flash Point: 216.4°C
• Density: 1.13g/cm³
• Vapor Pressure: 9.65E-08mmHg at 25°C
• Refractive Index: 1.578
• CAS DataBase Reference: N-cyclohexyl-P,P-diphenylphosphinic amide(CAS DataBase Reference)
• NIST Chemistry Reference: N-cyclohexyl-P,P-diphenylphosphinic amide(6941-20-4)
• EPA Substance Registry System: N-cyclohexyl-P,P-diphenylphosphinic amide(6941-20-4)

Safety Data

• Hazardous Substances Data: 6941-20-4(Hazardous Substances Data)

Upstream product

• 110-82-7 cyclohexane 
• 5994-87-6 diphenylphosphinamide 
• 100-64-1 cyclohexanone-oxime 
• 1079-66-9 chloro-diphenylphosphine 
• 108-91-8 cyclohexylamine 
• 67764-53-8 N-Cyclohexylidendiphenylphosphinamid 
• 1499-21-4 Diphenylphosphinic chloride 

Downstream Products

• 10108-56-2 N-butylcyclohexylamine 
• 4383-25-9 N-benzylcyclohexylamine 
• 6628-00-8 N-Allylcyclohexylamin 
• 62316-76-1 N-cyclohexyl-N-methyl-P,P-diphenylphosphinic amide 
• 63528-27-8 C₂₁H₂₆NOP 
• 63528-28-9 C₂₅H₂₈NOP 
• 63528-26-7 C₂₂H₃₀NOP 

Relevant articles and documents

Two new phosphinic amides: Synthesis, crystal structure, and theoretical study of hydrogen bonding

Two novel phosphinic amides, (C6H5)2P(O)(NH?cyclo?C7H13) (I) and (C6H5)2P(O)(NH?cyclo?C6H11) (II) were synthesized and characterized by spectrosc

Copper(II)-Photocatalyzed N-H Alkylation with Alkanes

We report a practical method for the alkylation of N-H bonds with alkanes using a photoinduced copper(II) peroxide catalytic system. Upon light irradiation, the peroxide serves as a hydrogen atom transfer reagent to activate stable C(sp3)-H bonds for the reaction with a broad range of nitrogen nucleophiles. The method enables the chemoselective alkylation of amides and is utilized for the late-stage functionalization of N-H bond containing pharmaceuticals with good to excellent yields. The mechanism of the reaction was preliminarily investigated by radical trapping experiments and spectroscopic methods.

SOME NEW PHOSPHINIC AMIDES R2P(O)NHR'

P,P-Diorganylphosphinic amides R2P(O)NHR' (R = tBu, iPr, Ph; R' = Et, Pr, Cy, iPr, tBu, Ph, etc.) have been prepared by reaction of R2PCl with the corresponding lithiated amine followed by oxidation with H2O2.Th