69411-05-8

Usage

Uses

Used in Pharmaceutical Industry:
3-AMINO-5-CHLOROBENZOTRIFLUORIDE is used as an intermediate in the synthesis of various pharmaceuticals for its ability to contribute to the development of new drugs with improved therapeutic properties.
Used in Agrochemical Industry:
3-AMINO-5-CHLOROBENZOTRIFLUORIDE is used as an intermediate in the production of agrochemicals, such as pesticides, to enhance crop protection and increase agricultural productivity.
Used in Dye and Pigment Industry:
3-AMINO-5-CHLOROBENZOTRIFLUORIDE is used as a building block in the manufacture of dyes and pigments, contributing to the creation of a diverse range of colorants for various applications.
Used in Organic Synthesis:
3-AMINO-5-CHLOROBENZOTRIFLUORIDE is used as a reagent in organic synthesis, facilitating the formation of new chemical compounds and contributing to the advancement of chemical research.
Used in the Preparation of Benzotrifluoride Derivatives:
3-AMINO-5-CHLOROBENZOTRIFLUORIDE is used as a starting material for the preparation of other functionalized benzotrifluoride derivatives, expanding the scope of chemical compounds available for various applications.

InChI:InChI=1/C7H5ClF3N/c8-5-1-4(7(9,10)11)2-6(12)3-5/h1-3H,12H2

Upstream product

• 401-93-4 5-chloro-3-trifluoromethyl-nitrobenzene 

Downstream Products

• 300842-56-2 1-(5-Chloro-3-trifluormethyl-anilino)-4-(4-pyridyl-methyl)-phthalazine 
• 941604-45-1 1-(3-Chloro-5-trifluoromethyl-phenyl)-3-(4-chloro-3-trifluoromethyl-phenyl)-urea 
• 884340-21-0 phenyl 3-chloro-5-(trifluoromethyl)phenylcarbamate 
• 349-63-3 acetic acid-(3-chloro-5-trifluoromethyl-anilide) 
• 24095-92-9 C₉H₉ClF₃N₃S 
• 96406-91-6 (3-Chloro-5-trifluoromethyl-phenyl)-hydrazine 
• 1510832-80-0 C₂₆H₃₇ClF₃N₃O₆ 
• 875167-01-4 3-chloro-5-(trifluoromethyl)benzene-1-sulfonyl chloride 
• 102583-95-9 N-(3-chloro-5-(trifluoromethyl)phenyl)anthranilic acid 
• 147494-44-8 tert-butyl 3-chloro-5-(trifluoromethyl)phenylcarbamate 

Relevant academic research and scientific papers

FUSED HETEROCYCLIC COMPOUNDS USEFUL AS MODULATORS OF NUCLEAR HORMONE RECEPTOR FUNCTION

Disclosed are fused heterocyclic compounds of Formula (I) or pharmaceutically-acceptable salts or stereoisomers thereof. Also disclosed are methods of using such compounds in the treatment of at least one androgen receptor-associated condition, such as, for example, cancer, and pharmaceutical compositions comprising such compounds.

Pyridine derivatives inhibiting angiogenesis and/or vegf receptor tyrosine kinase

The invention relates to pyridine derivatives of formula (I), wherein the substituents and symbols are defined as indicated in the description, processes for the preparation thereof, their usage in the preparation of a pharmaceutical composition for the treatment of a disease which responds to an inhibition of angiogenesis, and pharmaceutical compositions containing such compounds.

Isoquinoline derivatives with angiogenesis inhibiting activity

The invention relates to compounds of formula I wherein r is from 0 to 2; n is from 0 to 2; m is from 0 to 4; A, B, D and E are each independently of the others N or CH, with the proviso that not more than two of those radicals are N; G is lower alkylene, —CH2—O—, —CH2—S—, —CH2—NH—, oxa (—O—), thia (—S—) or imino (—NH—), or is lower alkylene substituted by acyloxy or by hydroxy; Q is lower alkyl, especially methyl; R is H or lower alkyl; X is imino, oxa or thia; Y is lower alkyl or, especially, aryl, heteroaryl or unsubstituted or substituted cycloalkyl; and Z is amino, mono- or di-substituted amino, halogen, alkyl, substituted alkyl, hydroxy, etherified or esterified hydroxy, nitro, cyano, carboxy, esterified carboxy, alkanoyl, carbamoyl, N-mono- or N,N-di-substituted carbamoyl, amidino, guanidino, mercapto, sulfo, phenylthio, phenyl-lower alkylthio, alkylphenylthio, phenylsulfinyl, phenyl-lower alkylsulfinyl, alkylphenyl-sulfinyl, phenylsulfonyl, phenyl-lower alkanesulfonyl or alkylphenylsulfonyl, and where, if more than one radical Z is present (m≧4), the substituents Z are identical or different; and wherein the bonds indicated by a wavy line are either single bonds or double bonds; or an N-oxide of the mentioned compound, wherein one or more N atoms carry an oxygen atom; or a salt thereof. The compounds inhibit especially angiogenesis.

Pyridazinedione compounds useful in treating neurological disorders

The present invention relates to pyridazino[4,5-b]quinolines, and pharmaceutically useful salts thereof, which are excitatory amino acid antagonists and which are useful when such antagonism is desired such as in the treatment of neurological disorders. The invention further provides pharmaceutical compositions containing pyridazino[4,5-b]quinolines as active ingredient, and methods for the treatment of neurological disorders.