69423-39-8Relevant academic research and scientific papers
Syntheses via Isoxazolines, 6. - Asymmetric Induction in the Reduction of 2-Isoxazolines to Yield γ-Amino Alcohols with Two or Three Vicinal Stereocentres
Jaeger, Volker,Buss, Volker,Schwab, Wilfried
, p. 122 - 139 (2007/10/02)
The substituted 3-aminopropanols 3 and 5 with two or three adjacent chiral centres are prepared from alkenes and nitrile oxides via LiAlH4 reduction of intermediate isoxazolines 2 and 4, respectively, in a regio- and stereoselective mode. 4-Alkyl groups g
