6943-96-0

Basic information

• Product Name: ethyl (2E)-2-(hydroxyimino)-3-phenylpropanoate
• CAS NO: 6943-96-0
• Molecular Formula: C₁₁H₁₃NO₃
• Molecular Weight: 207.2258
• Mol File: 6943-96-0.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 347.9°C at 760 mmHg
• Flash Point: 164.2°C
• Density: 1.11g/cm³
• Vapor Pressure: 1.96E-05mmHg at 25°C
• Refractive Index: 1.52
• CAS DataBase Reference: ethyl (2E)-2-(hydroxyimino)-3-phenylpropanoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl (2E)-2-(hydroxyimino)-3-phenylpropanoate(6943-96-0)
• EPA Substance Registry System: ethyl (2E)-2-(hydroxyimino)-3-phenylpropanoate(6943-96-0)

Safety Data

• Hazardous Substances Data: 6943-96-0(Hazardous Substances Data)

Upstream product

• 109-95-5 ethyl nitrite 
• 141-52-6 sodium ethanolate 
• 620-79-1 Ethyl 2-benzylacetoacetate 
• 544-16-1 n-Butyl nitrite 
• 607-81-8 diethyl 2-benzylmalonate 
• 100-44-7 benzyl chloride 

Downstream Products

• 100373-20-4 2-acetoxyimino-3-phenyl-propionic acid ethyl ester 
• 77426-83-6 2-[(E)-Hydroxyimino]-N-methyl-3-phenyl-propionamide 
• 1795-98-8 rac-phenylalaninol 
• 851769-57-8 ethyl 2-butyloxyimine-3-phenylpropionate 
• 851769-54-5 ethyl 2-ethyloxyimine-3-phenylpropionate 
• 851769-58-9 ethyl 2-dodecyloxyimino-3-phenylpropionate 
• 2901-75-9 (R,S)-N-acetyl phenylalanine 
• 150-30-1 Phenylalanine 
• 1345344-06-0 (E)-cyclo[N-benzyloxy-2-(phenylmethylene)glycylprolyl] 
• 1345344-04-8 (E)-cyclo[N-butyloxy-2-(phenylmethylene)glycylprolyl] 
• 1345343-90-9 N-(α-benzyloxime-3-phenylpropionyl)proline 
• 1345343-88-5 N-(α-n-butyloxime-3-phenylpropionyl)proline 
• 1345343-86-3 N-(α-methyloxime-3-phenylpropionyl)proline 
• 1345343-84-1 N-(α-cyclohexyloxime-3-phenylpropionyl)proline 

Relevant articles and documents

Unnatural α-amino ethyl esters from diethyl malonate or ethyl β-bromo-α-hydroxyiminocarboxylate

We have explored here the scope of the age-old diethyl malonate-based accesses to α-amino esters involving Knoevenagel condensations of diethyl malonate on aldehydes, reductions of the resulting alkylidenemalonates, the preparation of the corresponding α-hydroxyimino esters and their final reduction. This synthetic pathway turned out to be general although some unexpected limitations were encountered. The synthetic modifications of some of the intermediates - using Suzuki-Miyaura coupling or cycloadditions - before undertaking the oximation step - provided accesses to further α-amino esters. Moreover, other pathways to α-hydroxyimino esters were explored including an attempt to improve the cycloadditions between ethyl β-bromo-α-hydroxyiminocarboxylate and various alkylfuranes.

Nano-K2CO3: Preparation, characterization and evaluation of reactive activities

A novel base, nano-K2CO3, was easily prepared by ultrafine wet milling. The surface properties and the reactive activities of nano-K2CO3 were characterized. It was found that such a base showed higher basicity than normal K2CO3 and could replace sodium (or potassium) alkoxide to carry out monoalkylation and oximation of active methylene compounds. The nano-K2CO3 could be regenarated and reused 10 times without loss of its reactive activity.

Design, synthesis, and anti-tumor activity of (2-O-alkyloxime-3-phenyl)- propionyl-1-O-acetylbritannilactone esters

The extracts of Inula britannica have anti-inflammatory, anti-bacterial, anti-hepatitic, and anti-tumor activities. Various sesquiterpene lactones with cytotoxic properties including 1-O-acetylbritannilactone (1) have been isolated from this Chinese medic