694527-76-9

Upstream product

• 308279-67-6 (S)-3-Benzyloxy-2-((2S,3R)-2-tert-butoxycarbonylamino-3-methyl-pentanoylamino)-propionic acid allyl ester 
• 13139-16-7 Boc-L-aIle-OH 
• 15761-39-4 1-(tert-butoxycarbonyl)-L-proline 

Downstream Products

• 694528-00-2 N-((2R,3R)-3-[Boc-L-allo-Thr(TBS)-GlyO]-2-methylnonanoyl)-L-Pro-L-allo-Ile-L-Ser(Bn)-OAllyl 
• 742062-96-0 (S)-3-Benzyloxy-2-{(2S,3R)-2-[((S)-1-{(2R,3R)-3-[2-((2S,3S)-2-tert-butoxycarbonylamino-3-hydroxy-butyrylamino)-acetoxy]-2-methyl-nonanoyl}-pyrrolidine-2-carbonyl)-amino]-3-methyl-pentanoylamino}-propionic acid 
• 694527-64-5 (5R,6R,12S,15S,18S,20aS)-15-Benzyloxymethyl-18-((R)-sec-butyl)-6-hexyl-12-((S)-1-hydroxy-ethyl)-5-methyl-tetradecahydro-7-oxa-3a,10,13,16,19-pentaaza-cyclopentacyclononadecene-4,8,11,14,17,20-hexaone 
• 694527-86-1 N-((2R,3R)-3-hydroxy-2-methylnonanoyl)-L-Pro-L-allo-Ile-L-Ser(Bn)-OAllyl 

Relevant academic research and scientific papers

Structure-activity relationships of globomycin analogues as antibiotics

Globomycin (1a), a signal peptidase II inhibitor, and its derivatives show potent antibacterial activity against Gram-negative bacteria. The synthesis and antimicrobial activity of novel globomycin analogues are reported. The hydroxyl group in the L-Ser r