694527-87-2

Upstream product

• 308279-65-4 (+)-(2R,3R)-3-hydroxy-2-methylnonanoic acid 
• 694527-79-2 L-homo-Pro-L-allo-Ile-L-Ser(Bn)-OAllyl 
• 694527-78-1 (S)-2-[(1S,2R)-1-((S)-1-Allyloxycarbonyl-2-benzyloxy-ethylcarbamoyl)-2-methyl-butylcarbamoyl]-piperidine-1-carboxylic acid tert-butyl ester 
• 308279-67-6 (S)-3-Benzyloxy-2-((2S,3R)-2-tert-butoxycarbonylamino-3-methyl-pentanoylamino)-propionic acid allyl ester 

Downstream Products

• 694528-01-3 N-((2R,3R)-3-[Boc-L-allo-Thr(TBS)-GlyO]-2-methylnonanoyl)-L-homo-Pro-L-allo-Ile-L-Ser(Bn)-OAllyl 
• 742062-98-2 (S)-3-Benzyloxy-2-{(2S,3R)-2-[((S)-1-{(2R,3R)-3-[2-((2S,3S)-2-tert-butoxycarbonylamino-3-hydroxy-butyrylamino)-acetoxy]-2-methyl-nonanoyl}-piperidine-2-carbonyl)-amino]-3-methyl-pentanoylamino}-propionic acid 
• 694528-15-9 (6R,7R,13S,16S,19S,21aS)-16-Benzyloxymethyl-19-((R)-sec-butyl)-7-hexyl-13-((S)-1-hydroxy-ethyl)-6-methyl-tetradecahydro-8-oxa-4a,11,14,17,20-pentaaza-benzocyclononadecene-5,9,12,15,18,21-hexaone 

Relevant academic research and scientific papers

Structure-activity relationships of globomycin analogues as antibiotics

Globomycin (1a), a signal peptidase II inhibitor, and its derivatives show potent antibacterial activity against Gram-negative bacteria. The synthesis and antimicrobial activity of novel globomycin analogues are reported. The hydroxyl group in the L-Ser r