6946-28-7 Usage
Uses
Used in Pharmaceutical Industry:
N-sulfanilyl-L-glutamic acid is used as a starting material for the synthesis of various drugs, leveraging its unique structural properties to create a range of therapeutic compounds.
Used in Enzyme Inhibition:
It is utilized in the production of inhibitors for the enzyme dihydrofolate reductase, which is a significant target for the development of anticancer and antibiotic drugs. By inhibiting this enzyme, N-sulfanilyl-L-glutamic acid contributes to the disruption of essential metabolic pathways in disease-causing organisms.
Used in Medical Research:
N-sulfanilyl-L-glutamic acid is also employed in the study and potential treatment of various medical conditions. Its pharmacological properties are of ongoing interest to researchers, as they explore its potential to address a range of health issues.
Check Digit Verification of cas no
The CAS Registry Mumber 6946-28-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,9,4 and 6 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 6946-28:
(6*6)+(5*9)+(4*4)+(3*6)+(2*2)+(1*8)=127
127 % 10 = 7
So 6946-28-7 is a valid CAS Registry Number.
6946-28-7Relevant academic research and scientific papers
Possible antineoplastic agents, part XVII: Synthesis, antitumor and antiangiogenic study of few bioisosteres of thalidomide metabolites
Sen,Sarker,Ghosh,Mishra,Saha,Goswami,Gupta,De
, p. 1872 - 1878 (2012/09/22)
Two series of bioisostere of thalidomide metabolites and their cyclized variants were designed, synthesized and characterized. In vivo antitumor activity was studied on EAC in swiss albino mice. Cytotoxicity study was carried out on HUVEC and Vero cell lines by MTT assay method. Antiangiogenic activity on Ehrlich ascites tumor (EAT) was investigated studying inhibition of formation of micro vessels by identification of CD31 antigen through immunohistochemistry. One molecule has exhibited both antitumor and antiangiogenic activity but there is no significant toxic effect on normal cell.
