69461-07-0

Basic information

• Product Name: (6R)-6aβ,7,8,10aβ-Tetrahydro-7,7,9-trimethyl-11-[2-(methylamino)ethyl]-6β-[3-[2-(methylamino)ethyl]-1H-indol-2-yl]-6H-isoindolo[2,1-a]indole
• Synonyms: (6R)-6aβ,7,8,10aβ-Tetrahydro-7,7,9-trimethyl-11-[2-(methylamino)ethyl]-6β-[3-[2-(methylamino)ethyl]-1H-indol-2-yl]-6H-isoindolo[2,1-a]indole;Isoborreverine
• CAS NO: 69461-07-0
• Molecular Formula: C32H40N4
• Molecular Weight: 480.6868
• Mol File: 69461-07-0.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (6R)-6aβ,7,8,10aβ-Tetrahydro-7,7,9-trimethyl-11-[2-(methylamino)ethyl]-6β-[3-[2-(methylamino)ethyl]-1H-indol-2-yl]-6H-isoindolo[2,1-a]indole(CAS DataBase Reference)
• NIST Chemistry Reference: (6R)-6aβ,7,8,10aβ-Tetrahydro-7,7,9-trimethyl-11-[2-(methylamino)ethyl]-6β-[3-[2-(methylamino)ethyl]-1H-indol-2-yl]-6H-isoindolo[2,1-a]indole(69461-07-0)
• EPA Substance Registry System: (6R)-6aβ,7,8,10aβ-Tetrahydro-7,7,9-trimethyl-11-[2-(methylamino)ethyl]-6β-[3-[2-(methylamino)ethyl]-1H-indol-2-yl]-6H-isoindolo[2,1-a]indole(69461-07-0)

Safety Data

• Hazardous Substances Data: 69461-07-0(Hazardous Substances Data)

Usage

Occurrence

A complex alkaloid isolated from Flindersiafournieri.

Upstream product

• 61-54-1 tryptamine 
• 51076-19-8 (+/-)-Borrerine 
• 89759-48-8 methyl 1-(2-methylprop-1-enyl)-3,4-dihydro-1H-pyrido[3,4-b]indole-2(9H)-carboxylate 

Relevant articles and documents

Flindersia Alkaloids, Derivatives and Analogs: Compositions and Methods for Producing the Same

The present invention provides methods for chemically synthesizing naturally-occurring alkaloids, for example, Flindersia alkaloids, and their analogs and derivatives. Generally, the precursor borrerine is synthesized from tryptamine in the presence of an alkylating agent, an acylating agent and a reducing agent and dimerized in the presence of an acid, for example, tetrafluoroacetic acid, hydrochloric acid or acetic acid to yield the products. Analog and derivative compounds are produced by derivatizing one or more of the tryptamine, alkylating agent or acylating agent. Also provided are the synthetic alkaloids and derivatives and analogs thereof produced by the synthetic methods.