6947-38-2 Usage
Uses
Used in Biological Research:
N,N'-DIMETHYL-N,N'-DINITROSO-P-PHENYLENEDIAMINE is used as a caged, photolabile Nitric Oxide donor for delivering nitric oxide into intracellular compartments in a microsecond time scale without any cytotoxic effects. This makes it a valuable tool for studying the role of nitric oxide in various biological processes and its interaction with cellular components.
Used in Pharmaceutical Development:
As a stable and efficient NO donor, N,N'-DIMETHYL-N,N'-DINITROSO-P-PHENYLENEDIAMINE can be utilized in the development of pharmaceuticals targeting conditions where nitric oxide plays a crucial role, such as cardiovascular diseases, neurological disorders, and inflammatory conditions. Its rapid release and lack of cytotoxic effects make it a promising candidate for drug development.
Used in Drug Delivery Systems:
N,N'-DIMETHYL-N,N'-DINITROSO-P-PHENYLENEDIAMINE can be incorporated into drug delivery systems to improve the targeted delivery of nitric oxide to specific cells or tissues. This can enhance the therapeutic effects of nitric oxide and minimize potential side effects associated with its systemic administration.
Used in Analytical Chemistry:
The ability of N,N'-DIMETHYL-N,N'-DINITROSO-P-PHENYLENEDIAMINE to release nitric oxide upon irradiation makes it a useful tool in analytical chemistry for studying the properties and behavior of nitric oxide in various chemical reactions and processes.
Check Digit Verification of cas no
The CAS Registry Mumber 6947-38-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,9,4 and 7 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 6947-38:
(6*6)+(5*9)+(4*4)+(3*7)+(2*3)+(1*8)=132
132 % 10 = 2
So 6947-38-2 is a valid CAS Registry Number.
6947-38-2Relevant academic research and scientific papers
Highly selective sp3 C-N bond activation of tertiary anilines modulated by steric and thermodynamic factors
Jia, Xiaodong,Li, Pengfei,Shao, Yu,Yuan, Yu,Ji, Honghe,Hou, Wentao,Liu, Xiaofei,Zhang, Xuewen
supporting information, p. 5568 - 5574 (2017/12/06)
A highly selective sp3 C-N cleavage of tertiary anilines was achieved using the TBN/TEMPO catalyst system. When N,N-diaklylanilines (alkyl, benzyl) were employed, the N-CH3 bond was selectively cleaved via radical C-H activation. Moreover, when the allyl group was installed, totally reverse selectivity was observed. It is worth noting that the solvent effect is also crucial to obtain high reaction efficiency and selectivity.
