6952-91-6

Usage

Uses

Used in Organic Synthesis:
p-Cumenyl cyclopropyl ketone is utilized as a building block in organic synthesis for its ability to contribute to the formation of complex organic molecules. Its unique structure allows for the creation of a wide range of compounds with diverse properties.
Used in Pharmaceutical Research:
In the pharmaceutical industry, p-cumenyl cyclopropyl ketone serves as a valuable intermediate. It is employed in the development of new drugs, where its structural features can be leveraged to enhance the efficacy and selectivity of medicinal compounds.
Used in Chemical Industry:
p-Cumenyl cyclopropyl ketone is recognized for its potential in the design of novel organic molecules, making it a promising candidate for various applications within the chemical industry. Its versatility ensures that it can be adapted for use in multiple chemical processes and product development.

InChI:InChI=1/C13H16O/c1-9(2)10-3-5-11(6-4-10)13(14)12-7-8-12/h3-6,9,12H,7-8H2,1-2H3

Upstream product

• 70289-38-2 4-Chloro-1-(4-isopropyl-phenyl)-butan-1-one 

Downstream Products

• 873072-16-3 [4-(1-chloro-1-methyl-ethyl)-phenyl]-cyclopropyl-methanone 

Relevant academic research and scientific papers

PROCESS FOR CARBONYLATING PHENYLALKYL DERIVATIVES BY MEANS OF CARBON MONOXIDE

The invention is directed a process of preparing a compound of formula (I), wherein R1, R2, R3 and z are as defined herein.

METHOD FOR CARBONYLATING PHENYLALKYL DERIVATIVES BY MEANS OF CARBON MONOXIDE

The invention relates to a method for producing a phenylalkyl carboxylic acid of general formula (I), wherein identical or different R1 and R2 represent independently of each other -(C1-C4)-alkyl, Z is a hydrogen atom or -(CH2) n-CH3, wherein n=0 to 9, and R3 is-C(0)-(C1-C4)-alkyl which is substituted or not-substituted by CI or Br, only, or -C(0)-(C3-C6)-cycloalkyl, consisting in reacting a compound of formula (II), wherein X is Cl or Br or OH and R4 is defined as R2 rest represents jointly with X a C-C double bond with a carbon monoxide in the presence of a concentrated sulphuric acid, hydrogen fluoride or peracids and subsequently in adding water or alcohol of the formula CH3-(CH2)n-OH, wherein n=0 to 9.

Intermediates useful for the preparation of antihistaminic piperidine derivatives

The present invention is related to a novel intermediates and processes which are useful in the preparation of certain antihistaminic piperidine derivatives of the formula wherein W represents —C(═O)— or —CH(OH)—; R1represents hydrogen or hydroxy; R2represents hydrogen; R1and R2taken together form a second bond between the carbon atoms bearing R1and R2; n is an integer of from 1 to 5; m is an integer 0 or 1; R3is —COOH or —COOalkyl wherein the alkyl moiety has from 1 to 6 carbon atoms and is straight or branched; each of A is hydrogen or hydroxy; and pharmaceutically acceptable salts and individual optical isomers thereof, with the proviso that where R1and R2are taken together to form a second bond between the carbon atoms bearing R1and R2or where R1represented hydroxy, m is an integer 0.

Intermediates useful for the preparation of antihistaminic piperidine derivatives

The present invention is related to a novel intermediates and processes which are useful in the preparation of certain antihistaminic piperidine derivatives of the formula wherein W represents -C(=O)- or -CH(OH)-; R1 represents hydrogen or hydroxy; R2 represents hydrogen; R1 and R2 taken together form a second bond between the carbon atoms bearing R1 and R2; n is an integer of from 1 to 5; m is an integer 0 or 1; R3 is -COOH or -COOalkyl wherein the alkyl moiety has from 1 to 6 carbon atoms and is straight or branched each of A is hydrogen or hydroxy; and pharmaceutically acceptable salts and individual optical isomers thereof, with the proviso that where R1 and R2 are ta to form a second bond between the carbon R1 and R2 or where R1 represented hydroxy integer 0.