69540-12-1Relevant articles and documents
Syntheses of imidazoline-2-thiol-derivatives with potential tuberculostatic activity. I. Reactions of imidazoline-2-thiol with some isocyanates and isothiocyanates
Sawlewicz,Wisterowicz,Janowiec
, p. 403 - 411 (2007/10/08)
Imidazoline-2-thiol was reacted with aromatic isocyanates or isothiocyanates to yield respective N-arylcarbamyl and N-arylthiocarbamyl derivatives. The obtained compounds were subjected to cyanoethylation and aminomethylation reactions. The performed syntheses afforded 34 new derivatives of imidazoline-2-thiol, structures of which have been confirmed by elementary and spectral analysis. Tuberculostatic activity of the compounds was examined.