69558-02-7Relevant academic research and scientific papers
A mild and convenient indium(III) chloride-catalyzed synthesis of thioglycosides
Das, Saibal Kumar,Roy, Joyita,Reddy, Kalusani Anantha,Abbineni, Chandrasekhar
, p. 2237 - 2240 (2003)
The efficiency of glycosidation reactions generally involves a high chemical yield, as well as high/complete stereo- and regioselectivity. All these depend on the compatibility of the reactivity of glycosyl donors and acceptors. Among glycosyl donors, thi
METHOD FOR PREPARING 2'-O-FUCOSYLLACTOSE
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Page/Page column 24; 29; 30, (2017/09/27)
The present invention relates to a method for preparing 2'-O-fucosyllactose and to the protected fucosyl donor of the formula (I) used in this method. The method comprises reacting the fucose derivative of the formula (I) below with the compound of the ge
Synthesis of the tetrasaccharide glycoside moiety of Solaradixine and rapid NMR-based structure verification using the program CASPER
Angles d'Ortoli, Thibault,Widmalm, G?ran
, p. 912 - 927 (2016/01/28)
The major glycoalkaloid in the roots of Solanum laciniatum is Solaradixine having the branched tetrasaccharide β-d-Glcp-(1→2)-β-d-Glcp-(1→3)[α-l-Rhap-(1→2)]-β-d-Galp linked to O3 of the steroidal alkaloid Solasodine. We herein describe the synthesis of th
INFLAMMATION IMAGING AND THERAPY
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Page/Page column 23, (2014/03/22)
An imaging agent comprising a conjugate of an oligosaccharide moiety with an imaging moiety. The oligosaccharide is Lewis A or Lewis B or a mimetic thereof, or a pharmaceutically acceptable salt or PEGylated form of Lewis A or Lewis B or its mimetics. Lewis A and Lewis B and its mimetics are also provided for use in the therapeutic treatment of inflammatory diseases, autoimmune diseases and cancer.
The synthesis and biological evaluation of mycobacterial p-hydroxybenzoic acid derivatives (p-HBADs)
Bourke, Jean,Brereton, Corinna F.,Gordon, Stephen V.,Lavelle, Ed C.,Scanlan, Eoin M.
, p. 1114 - 1123 (2014/02/14)
Mycobacterium tuberculosis establishes chronic infection and causes disease through manipulation of the host's innate and adaptive immune response. The bacterial cell wall is highly complex and contains a rich variety of glycosylated compounds that are se
Synthesis of benzaldehyde-functionalized LewisX trisaccharide analogs for glyco-SAM formation
Kopitzki, Sebastian,Dilmaghani, Karim Akbari,Thiem, Joachim
, p. 10621 - 10636 (2013/11/19)
LewisX (Lex) antigen based carbohydrate-carbohydrate interactions are mediated by complexation of metal ions. Although theoretical studies about the influence of participating hydroxyl groups in the Le x trisaccharide head group (Gal
A coordinated synthesis and conjugation strategy for the preparation of homogeneous glycoconjugate vaccine candidates
Grayson, Elizabeth J.,Bernardes, Goncalo J. L.,Chalker, Justin M.,Boutureira, Omar,Koeppe, Julia R.,Davis, Benjamin G.
supporting information; experimental part, p. 4127 - 4132 (2011/07/07)
A sweet solution: A strategy for the synthesis of well-defined carbohydrate-based vaccines is presented. The approach couples complex oligosaccharide synthesis to site-specific conjugation methodology to provide pure glycoprotein vaccine candidates (see scheme). Copyright
Chemoenzymatic synthesis of naturally occurring benzyl 6-O-glycosyl-β- D-glucopyranosides
Kawahara, Eiji,Fujii, Mikio,Kato, Keisuke,Ida, Yoshiteru,Akita, Hiroyuki
, p. 1058 - 1061 (2007/10/03)
Direct β-glucosidation between benzyl alcohol and D-glucose (5) using the immobilized β-glucosidase from almonds with the synthetic prepolymer ENTP-4000 gave a benzyl β-D-glucoside (1) in 53% yield. The coupling of the benzyl β-D-glucopyranoside congener
InCl3 as a powerful catalyst for the acetylation of carbohydrate alcohols under microwave irradiation
Das, Saibal Kumar,Reddy, K. Anantha,Krovvidi, V. L. Narasimha Rao,Mukkanti
, p. 1387 - 1392 (2007/10/03)
Indium(III) chloride catalyzed microwave assisted acetylation of different carbohydrates is an efficient synthesis of per-O-acetyl derivatives and provides the products in good to excellent yields.
SPECIFIC ANTAGONIST FOR BOTH E- AND P-SELECTINS
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Page/Page column 10/22, (2010/02/11)
Compounds and methods are provided for modulating in vitro and in vivo processes mediated by selectin binding. More specifically, selectin modulators and their use are described, wherein the selectin modulators that modulate (e.g., inhibit or enhance) a selectin-mediated function comprise a particular glycomimetic linked to a particular BASA (Benzyl Amino Sulfonic Acid).
