69560-36-7

Upstream product

• 4460-86-0 asaraldehyde 
• 498-02-2 1-(3-methoxy-4-hydroxyphenyl)ethanone 
• 1131-62-0 1-(3,4-dimethoxyphenyl)ethanone 
• 120-14-9 3,4-dimethoxy-benzaldehyde 
• 5653-65-6 1-(3,4-dimethoxyphenyl)ethanol 
• 135-77-3 1,2,4-trimethoxy-benzene 
• 151-50-8 potassium cyanide 
• 88775-54-6 2,3',4,4',5-pentamethoxychalcone 

Downstream Products

• 88775-72-8 4-(3,4-dimethoxyphenyl)-4-oxo-2-(2,4,5-trimethoxyphenyl)butenoic acid 
• 88775-61-5 4-(3,4-dimethoxyphenyl)-4-oxo-2-(2,4,5-trimethoxyphenyl)butyric acid 
• 88775-57-9 4-(3,4-dimethoxyphenyl)-4-oxo-2-(2,4,5-trimethoxyphenyl)butyramide 
• 69560-42-5 6,7-dimethoxy-2-(2,4,5-trimethoxyphenyl)-3,4-dihydronaphthalen-1(2H)-one 
• 69560-40-3 4-(3,4-dimethoxyphenyl)-2-(2,4,5-trimethoxyphenyl)butyric acid 

Relevant academic research and scientific papers

Studies on the chemical constituents of rutaceous plants. XLIX. Development of a versatile method for the synthesis of antitumor-active benzo[c]phenanthridine alkaloids. (1). Preparation of various 2,4-bisaryl-4-oxobutyronitriles and 2,4-bisaryl-4-oxobutyramides

For the sake of establishment of a versatile synthetic method for benzo[c]phenanthridine alkaloids, improvement of the Robinson synthetic method was examined. Thirteen chalcones (7a-m) were prepared by condensation of two acetophenone derivatives (15 and 16) with eleven benzaldehyde derivatives (19a-k) as fundamental starting materials. Hydrocyanation of these chalcones (7a-1) except one (7m) gave the corresponding 2,4-bisaryl-4-oxobutyronitriles (8a-1). Eleven 2,4-bisaryl-4-oxobutyramides (9a-k) were also prepared.