69563-07-1

Upstream product

• 98-16-8 3-trifluoromethylaniline 
• 76-05-1 trifluoroacetic acid 
• 2946-73-8 2,2,2-trifluoro-N-(3-(trifluoromethyl)phenyl)acetamide 

Downstream Products

• 1353778-33-2 2,2,2-trifluoro-N'-(3-(trifluoromethyl)phenyl)acetamidine 
• 392-36-9 C₉H₄F₆N₂ 
• 392-36-9 2,4-bis(trifluoromethyl)-1H-benzo[d]imidazole 
• 399-69-9 2,5-bis(trifluoromethyl)-1H-benzo[d]imidazole 
• 1357114-27-2 5-methyl-2-(trifluoromethyl)-1-(3-(trifluoromethyl)phenyl)-1H-imidazole 
• 2946-73-8 2,2,2-trifluoro-N-(3-(trifluoromethyl)phenyl)acetamide 
• 1448786-48-8 C₁₈H₁₀F₆N₂O 
• 1236874-56-8 C₉H₅F₆NS 

Relevant academic research and scientific papers

Annulation of CF3-Imidoyl Sulfoxonium Ylides with 1,3-Dicarbonyl Compounds: Access to 1,2,3-Trisubstituted 5-Trifluoromethylpyrroles

A lithium-bromide-promoted nucleophilic substitution/annulation cascade reaction between CF3-imidoyl sulfoxonium ylides and 1,3-dicarbonyl compounds has been established, and the corresponding 1,2,3-trisubstituted 5-trifluoromethylpyrroles have been obtai

TiO2-Nanoparticles Catalyzed Synthesis of New Trifluoromethyl-4,5-dihydro-1,2,4-oxadiazoles and Trifluoromethyl-1,2,4-oxadiazoles

Synthesis of a new series of trifluoromethyl-4,5-dihydro-1,2,4-oxadiazoles and trifluoromethyl-1,2,4-oxadiazoles have been described by utilizing the reactions between amidoximes and trifluoroacetimidoyl chlorides. Trifluoromethyl-4,5-dihydro-1,2,4-oxadia

Synthesis of new (trifluoromethyl)-1H-benzo[e][1,2,4]triazolo[1,2-a][1,2,4]triazine-1,3(2H)-diones and (trifluoromethyl)benzo[5,6][1,2,4]triazino [1,2-b]phthalazine-8,13-diones

In this paper we investigated reactions of urazole and phthalazine with N-(aryl)-2,2,2-trifluoroacetimidoyl chloride derivatives. Results showed that when imidoyl chloride derivative has a fluorine atom at ortho position (3a–c), in two steps under a Ssub

A Facile Synthesis of New L-Proline-Based Trifluoromethyl Oxazole Derivatives Using Microwave Irradiation and Conventional Method

Cyclization reaction of l-proline with trifluoroacetimidoyl chlorides has been developed as an efficient strategy for the synthesis of trifluoromethyl oxazole derivatives by two methods: (a) in the presence of K2CO3 as a base in acet

One-pot synthesis of novel (2R,4S)-N-aryl-4-hydroxy-1-(2,2,2-trifluoroacetyl) pyrrolidine-2-carboxamides via TiO 2 -NPs and Pd(PPh3)2Cl2 catalysts and investigation of their biological activities

Abstract: A new class of (2R,4S)-N-aryl-4-hydroxy-1-(2,2,2-trifluoroacetyl)pyrrolidine-2-carboxamide compounds was synthesized by a facile one-pot reaction of trans-4-hydroxy proline and trifluoroacetimidoyl chlorides in the presence of TiO 2-n

Synthesis of Trifluoromethylated Pyrroles via a One-Pot Three-Component Reaction

A novel synthesis of trifluoromethylated pyrroles is described from a one-pot, three-component reaction between N -aryl-2,2,2-trifluoroacetimidoyl chlorides, dimethyl or diethyl acetylene dicarboxylate, and isocyanides in dry dichloromethane without catal

Synthesis of new trifluoromethylated indole derivatives

New indole trifluoromethyl derivatives have been synthesized using the reaction of indole derivatives with different 2,2,2-trifluoro-N-arylacetimidoyl chlorides in the presence of NaH as a base in acetonitrile at room temperature under an N2 at