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8-oxo-7,8-dihydrodeoxyguanine (8-oxodG) is a significant DNA lesion that arises from the oxidation of the guanine base, leading to the formation of this highly mutagenic and cytotoxic compound. It is a critical biomarker for oxidative stress and DNA damage, as it can pair with both adenine and cytosine during DNA replication, potentially causing G:C to T:A transversions. The accumulation of 8-oxodG in DNA has been implicated in various diseases, including cancer and neurodegenerative disorders. Its detection and quantification are essential for understanding the role of oxidative stress in cellular dysfunction and aging, and for developing strategies to prevent or mitigate its harmful effects.

6957-76-2

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6957-76-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 6957-76-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,9,5 and 7 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 6957-76:
(6*6)+(5*9)+(4*5)+(3*7)+(2*7)+(1*6)=142
142 % 10 = 2
So 6957-76-2 is a valid CAS Registry Number.
InChI:InChI=1/C5H5N5O/c6-4-7-1-2-3(9-4)10-5(11)8-2/h1H,(H4,6,7,8,9,10,11)

6957-76-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-amino-7,9-dihydropurin-8-one

1.2 Other means of identification

Product number -
Other names 8-Oxo-7,8-dihydrodeoxyguanine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:6957-76-2 SDS

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6957-76-2Relevant academic research and scientific papers

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