69587-11-7

Basic information

• Product Name: 4-IODO-2,5-DIMETHOXYPHENETHYLAMINE
• Synonyms: 4-IODO-2,5-DIMETHOXYPHENETHYLAMINE;2,5-DIMETHOXY-4-IODO PHENETHYLAMINE;2-(4-IODO-2,5-DIMETHOXYPHENYL)ETHANAMINE;2,5-Dimethoxy-4-IodophenethylamineHydrochloride[Dd];4-Iodo-2,5-dimethoxyphenethyla;2,5-DIMETHOXY-4-IODPHENYLETHYLAMIN;4-Iodo-2,5-diMethoxyphenethylaMine hydrochloride;BenzeneethanaMine,4-iodo-2,5-diMethoxy-
• CAS NO: 69587-11-7
• Molecular Formula: C₁₀H₁₄INO₂
• Molecular Weight: 307.13
• Mol File: 69587-11-7.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 354.324 °C at 760 mmHg
• Flash Point: 168.089 °C
• Appearance: /
• Density: 1.567 g/cm³
• PKA: 9.42±0.10(Predicted)
• CAS DataBase Reference: 4-IODO-2,5-DIMETHOXYPHENETHYLAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-IODO-2,5-DIMETHOXYPHENETHYLAMINE(69587-11-7)
• EPA Substance Registry System: 4-IODO-2,5-DIMETHOXYPHENETHYLAMINE(69587-11-7)

Safety Data

• Hazardous Substances Data: 69587-11-7(Hazardous Substances Data)

Upstream product

• 1216821-16-7 tert-butyl N-[2-(2,5-dimethoxy-4-iodophenyl)ethyl]carbamate 
• 10538-49-5 3-(2,5-dimethoxyphenyl)propanoic acid 
• 108536-18-1 β-dimethoxy-2,5 phenyl nitro ethylene 
• 14438-63-2 1-(2,5-dimethoxyphenyl)-2-nitroethanol 
• 187389-19-1 N-trifluoroacetyl-2-(2,5-dimethoxyphenyl)-1-aminoethane 
• 3600-86-0 2,5-dimethoxyphenethylamine 
• 40276-11-7 (E)-1,4-dimethoxy-2-(2-nitrovinyl) benzene 
• 159277-10-8 N-[2-(2,5-dimethoxy-4-iodophenyl)ethyl]-2,2,2-trifluoroacetamide 
• 64584-29-8 2-[2-(4-iodo-2,5-dimethoxyphenyl)ethyl]isoindole-1,3-dione 

Downstream Products

• 159277-10-8 N-[2-(2,5-dimethoxy-4-iodophenyl)ethyl]-2,2,2-trifluoroacetamide 
• 1216821-16-7 tert-butyl N-[2-(2,5-dimethoxy-4-iodophenyl)ethyl]carbamate 
• 919797-20-9 2-(((4-iodo-2,5-dimethoxyphenethyl)amino)methyl)phenol 
• 159277-08-4 1-(2,5-dimethoxy-4-(trufluoromethyl)phenyl)-2-aminoethane 

Relevant articles and documents

Synthesis of 25X-BOMes and 25X-NBOHs (X = H, I, Br) for pharmacological studies and as reference standards for forensic purposes

An expeditious method is reported for the synthesis of three NBOHs (25H-, 25I- and 25B-NBOH; 9–38% overall yield) and three NBOMes (25H-, 25I- and 25B-NBOMe; 7–33% overall yield) from salicylaldehyde and 2-methoxyaldehyde, respectively. The X-ray structures of 25H-, 25I- and 25B-NBOH.HCl were also determined. Our approach should provide a general entry for preparing such a class of substances for pharmacological and forensic purposes.

Synthesis and identification of metabolite biomarkers of 25C-NBOMe and 25I-NBOMe

Synthetic routes have been developed for synthesis of potential metabolites of 25C-NBOMe and 25I-NBOMe. Nine potential metabolites have been synthesized, among which compounds 8 and 20a could be used as metabolite biomarkers of 25C-NBOMe and 20b of 25I-NB

Synthesis of deuterium labeled phenethylamine derivatives

The synthesis of a series of five deuterium labeled phenethylamine derivatives, 4-bromo-2,5-[2H6]-dimethoxyphenethylamine (2C-B), 4-chloro-2,5-[2H6]-dimethoxyphenethylamine (2C-C), 2,5-[2H6]-dimethoxy-4-iodophenethylamine (2C-I), 2,5-[2H6]-dimethoxy-4-ethylthiophenethylamine (2C-T-2) and 2,5-[2H6]-dimethoxy-4-n-propylthiophenethylamine (2C-T-7) from 1,4-[2H6]-dimethoxybenzene is described. The isotopically labeled compounds are used as internal standards in gas chromatography-mass spectrometry (GC-MS) assays. Copyright