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69587-11-7Relevant academic research and scientific papers
Synthesis of 25X-BOMes and 25X-NBOHs (X = H, I, Br) for pharmacological studies and as reference standards for forensic purposes
Alves de Barros, Wellington,Queiroz, Marcelo Pereira,da Silva Neto, Leonardo,Borges, Graziele Martins,Martins, Felipe Terra,de Fátima, ?ngelo
supporting information, (2021/01/28)
An expeditious method is reported for the synthesis of three NBOHs (25H-, 25I- and 25B-NBOH; 9–38% overall yield) and three NBOMes (25H-, 25I- and 25B-NBOMe; 7–33% overall yield) from salicylaldehyde and 2-methoxyaldehyde, respectively. The X-ray structures of 25H-, 25I- and 25B-NBOH.HCl were also determined. Our approach should provide a general entry for preparing such a class of substances for pharmacological and forensic purposes.
Nanosensor for Sensitive Detection of the New Psychedelic Drug 25I-NBOMe
Alfonso, María,Díaz de Gre?u, Borja,Garrido, Eva,Gavi?a, Pablo,Lozano-Torres, Beatriz,Marcos, M. Dolores,Martínez-Má?ez, Ramón,Parra, Margarita,Sancenón, Félix
, (2020/02/27)
This work reports the synthesis, characterization, and sensing behavior of a hybrid nanodevice for the detection of the potent abuse drug 25I-NBOMe. The system is based on mesoporous silica nanoparticles, loaded with a fluorescent dye, functionalized with
Synthesis and identification of metabolite biomarkers of 25C-NBOMe and 25I-NBOMe
Wu, Xiongyu,Eriksson, Caroline,Wohlfarth, Ariane,Wallgren, Jakob,Kronstrand, Robert,Josefsson, Martin,Dahlén, Johan,Konradsson, Peter
, p. 6393 - 6400 (2017/10/16)
Synthetic routes have been developed for synthesis of potential metabolites of 25C-NBOMe and 25I-NBOMe. Nine potential metabolites have been synthesized, among which compounds 8 and 20a could be used as metabolite biomarkers of 25C-NBOMe and 20b of 25I-NB
4-Aryl-substituted 2,5-dimethoxyphenethylamines: Synthesis and serotonin 5-HT2A receptor affinities
Trachsel, Daniel,Nichols, David E.,Kidd, Stephanie,Hadorn, Marcel,Baumberger, Franz
experimental part, p. 692 - 704 (2010/04/23)
A series of novel ligands for the serotonin 5-HT2A/C receptor subtype bearing the 2-phenylethylamine pharmacophore was synthesized and assayed for its 5-HT2A receptor binding affinity. As the 4′-arylsubstituted 2-(2,5-dimethoxyphenyl
Synthesis of deuterium labeled phenethylamine derivatives
Xu, Ya-Zhu,Chen, Chinpiao
, p. 1187 - 1200 (2008/04/18)
The synthesis of a series of five deuterium labeled phenethylamine derivatives, 4-bromo-2,5-[2H6]-dimethoxyphenethylamine (2C-B), 4-chloro-2,5-[2H6]-dimethoxyphenethylamine (2C-C), 2,5-[2H6]-dimethoxy-4-iodophenethylamine (2C-I), 2,5-[2H6]-dimethoxy-4-ethylthiophenethylamine (2C-T-2) and 2,5-[2H6]-dimethoxy-4-n-propylthiophenethylamine (2C-T-7) from 1,4-[2H6]-dimethoxybenzene is described. The isotopically labeled compounds are used as internal standards in gas chromatography-mass spectrometry (GC-MS) assays. Copyright