696-06-0 Usage
Chemical Properties
White Solid
Uses
A metabolite of 5-Fluorouracil. (F596000)
Synthesis Reference(s)
The Journal of Organic Chemistry, 72, p. 8573, 2007 DOI: 10.1021/jo071255z
Check Digit Verification of cas no
The CAS Registry Mumber 696-06-0 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 6,9 and 6 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 696-06:
(5*6)+(4*9)+(3*6)+(2*0)+(1*6)=90
90 % 10 = 0
So 696-06-0 is a valid CAS Registry Number.
InChI:InChI=1/C4H5FN2O2/c5-2-1-6-4(9)7-3(2)8/h2H,1H2,(H2,6,7,8,9)
696-06-0Relevant articles and documents
Improved chemical syntheses of 5,6-dihydro-5-fluorouracil
LaFrate, Andrew L.,Katzenellenbogen, John A.
, p. 8573 - 8576 (2008/02/13)
(Chemical Equation Presented) 5,6-Dihydro-5-fluorouracil (5-DHFU) is a metabolite of the chemotherapy drug 5-fluorouracil (5-FU) of importance for biological studies. 5-DHFU has been prepared by enzymatic reduction of 5-FU and in very low yield by hydrogenation of 5-FU; however, a practical chemical synthesis is not available. Facile racemic syntheses of 5-DHFU from 5-FU or uracil, using p-methoxybenzyl protecting groups followed by L-Selectride reduction, are reported.
