69628-28-0

Basic information

• Product Name: 11-{[4-(tricyclo[3.3.1.1~3,7~]dec-1-ylmethyl)piperazin-1-yl]acetyl}-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one
• CAS NO: 69628-28-0
• Molecular Formula: C₂₉H₃₅N₅O₂
• Molecular Weight: 485.6205
• Mol File: 69628-28-0.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 652.2°C at 760 mmHg
• Flash Point: 348.2°C
• Density: 1.263g/cm³
• Vapor Pressure: 6.86E-17mmHg at 25°C
• Refractive Index: 1.628
• CAS DataBase Reference: 11-{[4-(tricyclo[3.3.1.1~3,7~]dec-1-ylmethyl)piperazin-1-yl]acetyl}-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one(CAS DataBase Reference)
• NIST Chemistry Reference: 11-{[4-(tricyclo[3.3.1.1~3,7~]dec-1-ylmethyl)piperazin-1-yl]acetyl}-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one(69628-28-0)
• EPA Substance Registry System: 11-{[4-(tricyclo[3.3.1.1~3,7~]dec-1-ylmethyl)piperazin-1-yl]acetyl}-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one(69628-28-0)

Safety Data

• Hazardous Substances Data: 69628-28-0(Hazardous Substances Data)

Usage

Chemical class

Benzodiazepine derivative

Known as

OPC-14523

Psychoactive properties

Sedative, hypnotic, anxiolytic, anticonvulsant, and muscle relaxant

Therapeutic applications

Potential use in treating neuropsychiatric disorders such as anxiety and mood disorders

Chemical structure

Unique structure with a tricyclic decylmethylpiperazine moiety and a pyrido[2,3-b][1,4]benzodiazepine core

Pharmacological profile

Promising candidate for further research and development in psychopharmacology

Molecular weight

Approximately 456.55 g/mol

Appearance

Likely a solid, possibly crystalline or amorphous

Solubility

Solubility properties may vary depending on the solvent, but generally soluble in organic solvents like methanol or dimethyl sulfoxide (DMSO)

Stability

May be sensitive to light, heat, and moisture, requiring storage under controlled conditions

Route of administration

The specific route of administration for OPC-14523 has not been mentioned, but benzodiazepines are typically administered orally or parenterally (e.g., intravenous, intramuscular)

Metabolism

The metabolism of OPC-14523 is not described in the provided material, but benzodiazepines are generally metabolized in the liver by the cytochrome P450 system

Excretion

The excretion of OPC-14523 is not described in the provided material, but benzodiazepines are typically excreted through the kidneys in the urine, with some metabolites being eliminated through the feces.

Relevant articles and documents

11-(Piperazino-acetyl)-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-ones and salts thereof

Compounds of the formula STR1 wherein R1 is alkyl of 3 to 12 carbon atoms; unsaturated aliphatic hydrocarbyl of 3 to 20 carbon atoms comprising 1 to 3 double bonds and/or one triple bond; phenyl(alkyl of 2 to 4 carbon atoms); methylenedioxybenz