69628-98-4

Basic information

• Product Name: 1-(2-methoxyethyl)-4-nitrobenzene
• Synonyms: 1-(2-methoxyethyl)-4-nitrobenzene;Methyl 2-(4-nitrophenyl)ethyl ether;Methyl[2-(4-nitrophenyl)ethyl] ether;p-Nitrophenethyl Methyl Ether;2-(4-nitrophenyl)ethyl methyl ether
• CAS NO: 69628-98-4
• Molecular Formula: C₉H₁₁NO₃
• Molecular Weight: 181.18854
• EINECS: 274-058-2
• Mol File: 69628-98-4.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 273.6 °C at 760 mmHg
• Flash Point: 120.6 °C
• Appearance: /
• Density: 1.154 g/cm³
• Vapor Pressure: 0.00949mmHg at 25°C
• Refractive Index: 1.533
• Storage Temp.: Refrigerator
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• CAS DataBase Reference: 1-(2-methoxyethyl)-4-nitrobenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-methoxyethyl)-4-nitrobenzene(69628-98-4)
• EPA Substance Registry System: 1-(2-methoxyethyl)-4-nitrobenzene(69628-98-4)

Safety Data

• Hazardous Substances Data: 69628-98-4(Hazardous Substances Data)

Usage

Uses

p-Nitrophenethyl Methyl Ether is an intermediate used in preparation of oxodihydropyridopyrimidines as c-fms kinase inhibitors which are useful in the treatment of diseases.

InChI:InChI=1/C9H11NO3/c1-13-7-6-8-2-4-9(5-3-8)10(11)12/h2-5H,6-7H2,1H3

Upstream product

• 100-27-6 2-(4-nitrophenyl)ethanol 
• 616-38-6 carbonic acid dimethyl ester 
• 74-88-4 methyl iodide 
• 77-78-1 dimethyl sulfate 
• 2945-08-6 methyl (4-nitrophenyl)acetate 
• 3558-60-9 1-methoxy-2-phenylethane 

Downstream Products

• 84803-56-5 4-(2-methoxyethyl)aniline 
• 102008-65-1 N,N'-bis-[4-(2-methoxy-ethyl)-phenyl]-thiourea 
• 102167-07-7 N-(4-butyl-phenyl)-N'-[4-(2-methoxy-ethyl)-phenyl]-thiourea 

Relevant articles and documents

Easy eco-friendly phenonium ion production from phenethyl alcohols in dimethyl carbonate

An efficient and simple one-pot procedure for selective etherification of 2-aryl-ethylalcohols has been achieved through Amberlyst 15-catalyzed reaction in dimethyl carbonate (DMC). Moreover, the polymer catalyst could be recovered and reused with no effect on its activity. The reaction mechanism involves the formation of phenonium ion which has been demonstrated by a C-C bond forming reaction. Theoretical studies are in agreement with and thus explain experimental results.

HALOETHYL UREA COMPOUNDS AND THEIR USE TO ATTENUATE, INHIBIT OR PREVENT NON-CANCEROUS PATHOGENIC CELLULAR PROLIFERATION AND DISEASES ASSOCIATED THEREWITH

The present invention provides haloethyl urea compounds as described in Formula (I) and their use as anti-proliferative agent in the attenuation, inhibition, or prevention of non-cancerous cellular proliferation. These compounds are also provided for use as a therapeutic agent in the treatment of a disease or disorder, wherein pathogenesis of said disease or disorder is associated with non-cancerous pathogenic cellular proliferation.

Reduction of carboxylic esters to ethers with triethyl silane in the combined use of titanium tetrachloride and trimethylsilyl trifluoromethanesulfonate

Aliphatic acyclic and cyclic ethers are prepared on treatment of their corresponding carboxylic esters and lactones with triethylsilane in the presence of titanium tetrachloride and trimethylsilyl trifluoromethanesulfonate.