6963-48-0Relevant academic research and scientific papers
Facile oxidative hydrolysis of acetals to esters using hypervalent iodine(III)/LiBr combination in water
Panchan, Waraporn,Chiampanichayakul, Supanimit,Snyder, Deanna L.,Yodbuntung, Siriporn,Pohmakotr, Manat,Reutrakul, Vichai,Jaipetch, Thaworn,Kuhakarn, Chutima
experimental part, p. 2732 - 2735 (2010/05/17)
The combination of (diacetoxy)iodobenzene (PhI(OAc)2, DIB) and lithium bromide (LiBr) efficiently oxidized cyclic and acyclic acetals to the corresponding hydroxyalkyl carboxylic esters and simple esters in good to excellent yields. The merits of this reaction are that it employs commercially available and non-explosive hypervalent iodine(III) reagent, water as the solvent, a short reaction time, and mild reaction conditions.
Oxone: A convenient reagent for the oxidation of acetals
Curini, Massimo,Epifano, Francesco,Marcotullio, Maria Carla,Rosati, Ornelio
, p. 777 - 779 (2007/10/03)
Symmetrical cyclic and acyclic acetals by oxidation with Oxone gave the corresponding esters in good yield. Treatment of tetrahydropyranyl derivatives of alcohols with the same reagent resulted in oxidative regeneration of the alcohols.
