6963-64-0Relevant academic research and scientific papers
IMIDOTHIAZOLE KINASE INHIBITORS
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Page/Page column 33, (2011/04/24)
The present invention is directed to novel kinase inhibitors of general formula (I) and pharmaceutically acceptable salts thereof, and to the use of the kinase inhibitors of general formula (I) for treating diseases or disorders in which tau phosphorylati
REACTIONS OF 4,5-DINITROIMIDAZOLE AND 4(5)-NITROIMIDAZOLE-5(4)-SULFONIC ACID WITH NUCLEOPHILES
Mokrushin, V. S.,Belyaev, N. A.,Kolobov, M. Yu.,Fedotov, A. N.
, p. 650 - 652 (2007/10/02)
The reactions of 4,5-dinitroimidazole and 5(4)-nitroimidazole-4(5)-sulfonic acid with nucleophilic agents were studied.Mercapto-, alkoxy-, and aminonitroimidazoles were synthesized.In the reaction of dinitroimidazole with sodium alkoxides 5(4)-nitroimidazole was obtained in addition to alkoxynitroimidazoles.It is shown that in the formation of salts of the starting imidazoles with bases nucleophilic-substitution reactions take place only with "soft" reagents.
