69649-28-1Relevant academic research and scientific papers
Iodosylbenzene Coordination Chemistry Relevant to Metal-Organic Framework Catalysis
Cardenal, Ashley D.,Maity, Asim,Gao, Wen-Yang,Ashirov, Rahym,Hyun, Sung-Min,Powers, David C.
, p. 10543 - 10553 (2019/09/13)
Hypervalent iodine compounds formally feature expanded valence shells at iodine. These reagents are broadly used in synthetic chemistry due to the ability to participate in well-defined oxidation-reduction processes and because the ligand-exchange chemist
Oxidase catalysis via aerobically generated hypervalent iodine intermediates
Maity, Asim,Hyun, Sung-Min,Powers, David C.
, p. 200 - 204 (2018/02/06)
The development of sustainable oxidation chemistry demands strategies to harness O'2 as a terminal oxidant. Oxidase catalysis, in which O'2 serves as a chemical oxidant without necessitating incorporation of oxygen into reaction products, would allow diverse substrate functionalization chemistry to be coupled to O'2 reduction. Direct O'2 utilization suffers from intrinsic challenges imposed by the triplet ground state of O'2 and the disparate electron inventories of four-electron O'2 reduction and two-electron substrate oxidation. Here, we generate hypervalent iodine reagents - a broadly useful class of selective two-electron oxidants - from O'2. This is achieved by intercepting reactive intermediates of aldehyde autoxidation to aerobically generate hypervalent iodine reagents for a broad array of substrate oxidation reactions. The use of aryl iodides as mediators of aerobic oxidation underpins an oxidase catalysis platform that couples substrate oxidation directly to O'2 reduction. We anticipate that aerobically generated hypervalent iodine reagents will expand the scope of aerobic oxidation chemistry in chemical synthesis.
Ortho-Metalated Aryl tert-Butyl Sulfones, Comparison with Other Directing Groups and New Methodology for Polysubstituted Aromatics
Iwao, M.,Iihama, T.,Mahalanabis, K. K.,Perrier, H.,Snieckus, V.
, p. 24 - 26 (2007/10/02)
The general utility of ortho-lithiated aryl tert-butyl sulfones for the synthesis of a variety of 2- and 2,6-carbon- and heteroatom-substituted products in good to excellent yields is described (Schemes I, VI, VII).
