696611-06-0Relevant articles and documents
Selective inhibition of glycosidases by feedback prodrugs
Guo, Jun,Asong, Jinkeng,Boons, Geert-Jan
, p. 5345 - 5348 (2006)
(Figure Presented) In the loop: A novel concept for the selective inhibition of glycosidases has been developed whereby a glycosidase inhibitor is released by glycosidase-mediated hydrolysis of a prodrug, which subsequently inhibits the glycosidase that i
FEEDBACK PRODRUG
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Page/Page column 19-20, (2008/06/13)
Compounds and methods for use in selectively inhibiting a lytic enzyme based on feedback inhibition. The conjugated compound serves as a substrate for a lytic enzyme. Cleavage of the conjugated compound by the lytic enzyme releases an inhibitor of the enz