696614-29-6Relevant articles and documents
Removal of the phosphate group in mechanism-based inhibitors of inositol monophosphatase leads to unusual inhibitory activity.
Miller, David J,Bashir-Uddin Surfraz,Akhtar, Mahmoud,Gani, David,Allemann, Rudolf K
, p. 671 - 688 (2007/10/03)
Inositol monophosphatase is widely held to be the therapeutic target for inhibition by lithium ion in the treatment of bipolar disorder. In a continued effort to improve the bioavailability of alternative inhibitors, we have designed and tested two new se