696640-55-8

Upstream product

• 36646-78-3 3-(p-tolylamino)-5,5-dimethylcyclohex-2-enone 
• 91-56-5 indole-2,3-dione 
• 109-77-3 malononitrile 

Relevant academic research and scientific papers

Efficient one-pot synthesis of spirooxindole derivatives bearing hexahydroquinolines using multicomponent reactions catalyzed by ethylenediamine diacetate

A simple and efficient one-pot synthesis of biologically interesting spirooxindole derivatives bearing hexahydroquinoline skeleton was accomplished by EDDA-catalyzed, three-component reactions between isatins, malononitrile, and enaminones in good yields. The value of this methodology lies in its inexpensive and nontoxic organocatalyst, mild reaction conditions, and ease of handling.

Microwave-assisted synthesis of new spiro[indoline-3,4'-quinoline] derivatives via a one-pot multicomponent reaction

A simple and efficient synthesis of spiro[indoline-3,4'-quinoline] derivatives by a one-pot reaction of isatin, malononitrile, and enaminone under microwave irradiation was investigated. This protocol has the advantages of short reaction time, high yields