696643-13-7

Upstream product

• 72345-23-4 (2S,4S)-pentane-2,4-diol 
• 6630-33-7 ortho-bromobenzaldehyde 

Downstream Products

• 695816-48-9 [2-((4S,6S)-dimethyl-[1,3]dioxan-2-yl)phenyl]phosphonic acid diethyl ester 
• 695816-49-0 [2-((4S,6S)-dimethyl-[1,3]dioxan-2-yl)phenyl]phosphane 
• 928209-93-2 1-[2-(4,6-dimethyl-[1,3]dioxan-2-yl)-phenyl]-2-nitro-ethanol 
• 928209-97-6 4,6-dimethyl-2-[2-(2-nitro-vinyl)-phenyl]-[1,3]dioxane 
• 928209-89-6 2-(4,6-dimethyl-[1,3]dioxan-2-yl)-benzaldehyde 

Relevant academic research and scientific papers

Fine-tuning monophosphine ligands for enhanced enantioselectivity. Influence of chiral hemilabile pendant groups

C2-Symmetric P-(2-X-aryl)-2,5-dialkylphospholanes (X = dioxolan-2-yl or dioxan-2-yl), designed on the basis of a working model for asymmetric induction, are effective ligands for the Ni(II)-catalyzed asymmetric hydrovinylation of styrenes. Excellent yields (>99%), selectivities for the desired 3-arylbutenes (>99%), high S/C ratios (>1200), and ee's (up to 91%) have been realized for a number of prototypical vinylarenes. In the dioxolane series, the selectivity depends on the configuration of the C 4 and C5 carbons.

Highly diastereoselective conjugate addition of aryllithium to chiral β-nitrostyrene derivative: An application to the asymmetric synthesis of 4-aryl-1,2,3,4-tetrahydroisoquinoline

Highly diastereoselective conjugate addition of aryllithium to β-nitrostyrene derivative, having chiral acetal moiety derived from (S,S)-1,2-bis(1-hydroxypropyl)benzene, was achieved. The adduct was transformed to 4-aryl-1,2,3,4-tetrahydroisoquinoline in