6969-16-0

Usage

Uses

Used in Flavor and Fragrance Industry:
2-Tridecenoic acid is used as a key intermediate for synthesizing flavor and fragrance compounds due to its unique chemical structure and properties. It contributes to the development of novel scents and tastes, enhancing the sensory experience in various consumer products.
Used in Pharmaceutical Industry:
2-Tridecenoic acid is utilized as a building block in the synthesis of pharmaceutical compounds. Its unique structure allows for the creation of new drugs with potential therapeutic applications, addressing unmet medical needs and improving patient outcomes.
Used in Chemical Synthesis:
2-Tridecenoic acid serves as an important intermediate in the chemical synthesis of various derivatives. Its versatile properties make it a valuable component in the development of new compounds with commercial and industrial applications, driving innovation and expanding the range of available products.

Upstream product

• 141-82-2 malonic acid 
• 112-44-7 undecylaldehyde 

Downstream Products

• 7774-82-5 tridecylenic aldehyde 
• 857079-00-6 2-tridecenoyl chloride 

Relevant academic research and scientific papers

Enantioselective Synthesis of N?H-Free 1,5-Benzothiazepines

An enantioselective sulfa-Michael-cyclization reaction was developed for the synthesis of 1,5-benzothiazepines with versatile pharmacological activities. The reaction between 2-aminothiophenol and α,β-unsaturated pyrazoleamides gave direct access to N?H-free 1,5-benzothiazepines in the presence of a chiral N,N′-dioxide/Yb(OTf)3complex. Excellent enantioselectivities (up to 96 % ee) and high yields (up to 99 %) were obtained for a broad range of substrates under mild reaction conditions. This method provided a facile approach to the antidepressant drug (R)-(?)-Thiazesim.

Application of chiral ligands: Carbohydrates, nucleoside-lanthanides and other Lewis acid complexes to control regio- and stereoselectivity of the dipolar cycloaddition reactions of nitrile oxides and esters

Chiral Lewis acid mediated 1,3-dipolar cycloaddition reactions of 4-trifluoromethylbenzonitrile oxide to methyl crotonate as well to β-substituted acrylates and (Z)-pent-2-en-1-yl esters were examined. Excellent enantioselectivities with moderate to good regioselectivities were achieved for crotonates with complexes of BiBr3 with (+)-(4,6-benzylidene)methyl-α-d-glucopyranoside C, with the l-ascorbic acid I-FeCl3 system, and with lipase Candida antarctica. High enantiomeric excess was observed for isopropyl ester and benzyl ester. The outstanding ee values were achieved for acrylates with β-t-butyl, cyclohexyl, and 1,3-benzodioxol-5-yl groups in cycloadditions catalyzed by C-Yb(OTf)3 and the (+)-2-hydroxy-3-pinanone N-TiCl4 system. High enantioselectivities were found in reactions of (Z)-pent-2-en-1-yl esters mediated by complexes N-Mg(OTf)2 and N-TiCl4.