69695-61-0

Usage

InChI:InChI=1/C7H5ClF3NO/c8-5-3-4(1-2-6(5)12)13-7(9,10)11/h1-3H,12H2

Upstream product

• 123-30-8 4-amino-phenol 
• 461-82-5 4-(trifluoromethoxy)aniline 

Downstream Products

• 79960-69-3 2-Chloro-1-isocyanato-4-trifluoromethoxy-benzene 
• 689300-85-4 (2-chloro-4-trifluoromethyl-phenyl)-methyl-amine 
• 858124-12-6 5-cyano-N-(4-trifluoromethoxy-2-chlorophenyl)-2-methoxybenzamide 
• 874482-94-7 2-chloro-4-(trifluoromethoxy)benzonitrile 
• 85578-47-8 2-chloro-1-nitro-4-(trifluoromethoxy)benzene 
• 1441345-82-9 tert-butyl 2-chloro-4-(trifluoromethoxy)phenylcarbamate 
• 658-89-9 4-(trifluoromethoxy)benzene-1,2-diamine 
• 1616415-66-7 phenyl N-[2-chloro-4-(trifluoromethoxy)phenyl] carbamate 
• 1380672-78-5 5-(2,2,2-trifluoro-ethoxy)-pyridine-2-carboxylic acid (2-chloro-phenyl)-amide 
• 1253972-24-5 N-{1-[6-(4-trifluoromethoxyphenylamino)naphthalen-2-yl]ethyl}acetamide 
• 748163-14-6 2-chloro-4-(trifluoromethoxy)benzene-1-sulfonyl chloride 

Relevant academic research and scientific papers

Preparation method of 4- polyfluoro methoxy O-phenylenediamine (by machine translation)

The method disclosed by the invention 4 - is characterized in that the aminophenol, and the alkali :(1) are reacted at a mole ratio of the 1:0.8-1.5, 20-40 °C compound 0.1-24h with the halogen, and, the halogen compound in the solvent to 1:1.0-3.0,20-120 °C, 0.01-20Mpa react with 1-72h. 1-72h the 4 - 1:0.8-30.0 ammonia solution ;(2)4 - or the halogen compound at a mole ratio of the compound of the 1:0.2 - 2.5 amino phenol, 30-80 °C with 0.1-24h;(3)4 - the halogen and the halogen compound in the solvent 0.1-10%, 50-200 °C, 0.01-10Mpa: 4 . (by machine translation)

Novel imidazopyrimidinyl and imidazopyri dinyl derivatives

Provided herein are compounds of the formula (I): 1 as well as stereoisomers and pharmaceutically acceptable salts thereof. Such compounds are, because of their ability to antagonize CRF, useful in the treatment of a variety of disorders characterized by