69705-29-9

Basic information

• Product Name: 4-Chloro-2-iodo-6-methylaniline 95+%
• Synonyms: 4-Chloro-2-iodo-6-methylaniline 95+%;4-Chloro-2-iodo-6-methylaniline;2-Amino-5-chloro-3-iodotoluene;Benzenamine, 4-chloro-2-iodo-6-methyl-
• CAS NO: 69705-29-9
• Molecular Formula: C₇H₇ClIN
• Molecular Weight: 267
• Mol File: 69705-29-9.mol
• Article Data: 10

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-Chloro-2-iodo-6-methylaniline 95+%(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Chloro-2-iodo-6-methylaniline 95+%(69705-29-9)
• EPA Substance Registry System: 4-Chloro-2-iodo-6-methylaniline 95+%(69705-29-9)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 69705-29-9(Hazardous Substances Data)

Usage

Description

4-Chloro-2-iodo-6-methylaniline 95+% is a chemical compound that is primarily used in pharmaceutical and organic synthesis. It is a highly pure form of the chemical, with a minimum purity of 95%. This derivative of aniline is known for its wide range of applications in the production of various drugs and medications.

Uses

Used in Pharmaceutical Industry:
4-Chloro-2-iodo-6-methylaniline 95+% is used as an intermediate in the synthesis of pharmaceuticals for its ability to contribute to the development of various drugs and medications.
Used in Pesticide Production:
In the agricultural sector, 4-Chloro-2-iodo-6-methylaniline 95+% is utilized as a component in the production of pesticides, playing a role in creating effective and targeted pest control solutions.
Used in Dye Manufacturing:
4-Chloro-2-iodo-6-methylaniline 95+% is also used in the manufacturing of dyes, where its unique properties contribute to the creation of a diverse range of colorants for various applications.
Used in Organic Synthesis:
4-Chloro-2-iodo-6-methylaniline 95+% is employed as a building block in organic synthesis, enabling the production of other organic compounds for research and commercial purposes.
Used in Research Processes:
Due to its high purity level, 4-Chloro-2-iodo-6-methylaniline makes a valuable and reliable chemical for use in research processes, facilitating the discovery and development of new chemical entities and their applications.

Upstream product

• 95-69-2 4-chloro-2-methylbenzeneamine 

Downstream Products

• 939990-03-1 2-amino-5-chloro-3-methylbenzonitrile 
• 644961-69-3 4-chloro-2-methoxy-6-methylphenylamine 

Relevant articles and documents

C?N Axial Chiral Hypervalent Iodine Reagents: Catalytic Stereoselective α-Oxytosylation of Ketones

A simple synthesis of a library of novel C?N axially chiral iodoarenes is achieved in a three-step synthesis from commercially available aniline derivatives. C?N axial chiral iodine reagents are rarely investigated in the hypervalent iodine arena. The potential of the novel chiral iodoarenes as organocatalysts for stereoselective oxidative transformations is assessed using the well explored, but challenging stereoselective α-oxytosylation of ketones. All investigated reagents catalyse the stereoselective oxidation of propiophenone to the corresponding chiral α-oxytosylated products with good stereochemical control. Using the optimised reaction conditions a wide range of products was obtained in generally good to excellent yields and with good enantioselectivities.

Revisiting the Gold-Catalyzed Dimerization of 2-Ethynylanilines: A Room-Temperature and Silver-Free Protocol for the Synthesis of Multifunctional Quinolines

A room temperature and silver-free protocol for the formation of quinolines from 2-ethynylanilines through a dimerization event was achieved using a dinuclear gold catalyst, Au2(BIPHEP)(NTf2)2. The reaction is inherently modular, allowing for the incorporation of peripheral substituents at any site of the quinoline product. The reaction is readily applied to other heterocyles also as exemplified by the preparation of naphthyridines. Competition reactions to determine the reactivity of dissimilar alkynes demonstrated that the product ratio of dimerization vs intermolecular addition is rather dependent on the electronic nature of aryl substituent on the alkynes. However, control experiments with substrates possessing internal alkynes resulted in cycloisomerization instead of expected dimerization, which is indicative of possible steric influence of the alkyne terminus in the reaction outcome.

QUINAZOLINEDIONE DERIVATIVE

The present invention relates to quinazolinedione derivatives represented by formula (I) or pharmaceutically acceptable salts thereof.