6971-48-8Relevant academic research and scientific papers
Novel two-step, one-pot synthesis of primary acylureas
Xiao, Zili,Yang, Michael G.,Tebben, Andrew J.,Galella, Michael A.,Weinstein, David S.
experimental part, p. 5843 - 5844 (2010/11/05)
A new procedure for the synthesis of primary acylureas from cyanamide and a variety of carboxylic acids is described. Under mild reaction conditions, the products were obtained in good yield from commercially available starting materials.
Nucleophilic substitution of urea on aromatic carboxylic acids via phosphorylation
Prabhakaran, P V,S, Jayadev,Nema, S K,Rao, K V C
, p. 1072 - 1073 (2007/10/02)
The nucleophilic substitution reaction of urea on aromatic carboxylic acids has been carried out via phosphorylation.Five different carboxylureas have been synthesised in good yields and with high purity.This new route makes the existing corrosive acid chloride route easier and can be used as a general route for the preparation of any acid-urea substitution product.The products have been characterized by elemeental analyses and spectral data (IR, PMR and mass).
