69719-37-5

Upstream product

• 207682-25-5 2,3-dilithio-4-methyl-1,1-pentamethylene-1,3-pentadiene 
• 36163-62-9 1,1-Pentamethylen-4-methyl-penta-1,2,3-trien 
• 5240-32-4 1-acetoxy-1-ethynyl cyclohexane 
• 13291-18-4 isopropenylmagnesium bromide 

Downstream Products

• 1234146-82-7 C₂₁H₂₅ClO₅ 

Relevant academic research and scientific papers

Concise approach to pupukeanane skeleton: Synthetic study of chloropupukeananin

A concise synthesis of a highly functionalized chloropupukeananin (1) skeleton via a reverse electron-demand Diels-Alder reaction and intramolecular carbonyl-ene reaction sequence based on our proposed biosynthetic pathway is described.

Controlled Rearrangement of 2,3-Dilithio-1,3-butadienes to 2,5-Dilithio-1,3-butadienes: Synthesis of 2-Isopropylidene-2,5-dihydrosilols

3,4-Dilithio-2,5-dimethyl-2,4-hexadiene (4a) rearranges to the cross-conjugated 2,5-dimethylhexadienediyl dianion 11a. A mechanistic investigation proves the intermolecularity of this rearrangement, which is also observed when starting from 4b. The 3-lithio-2,5-dimethylhexadienyl anion 10a with one vinyllithium and one allyllithium group, is a true intermediate in this rearrangement, its synthetic potential is employed in the reaction with dichlorosilanes to form 2-isopropylidene-2,5-dihydrosilols 8.