69720-12-3Relevant academic research and scientific papers
Synthesis, antibacterial and antioxidant properties of pyrazolylpyridazines
Ather, Abdul Qayuum,Chaudhry, Faryal,Khan, Muhammad Naeem,Bueno, Eliana Aparecida Silicz,Khan, Misbahul Ain,Aslam, Noreen,Khan, Khalid M.,Athar, Muhammad Makshoof,Munawar, Munawar Ali,Ashraf, Muhammad,Ejaz, Syeda Abida
, p. 7743 - 7748 (2013/09/23)
A number of 6-chloro-3-(pyrazol-1′-yl) pyridazines were prepared from 3,6-dichloropyridazine via either reaction with hydrazine followed I by reaction with appropriate reagents to develop the pyrazole or through a nucleophilic reaction with a pyrazole. So
Reactions of 3-Chloro-6-hydrazinopyridazine with Michael-retro-Michael Reagents
Sunder, Shyam,Peet, Norton P.
, p. 1527 - 1529 (2007/10/02)
Although pyrazole formation results from treatment of 3-chloro-6-hydrazinopyridazine (2) with both ethoxymethylenemalononitrile and ethyl (ethoxymethylene)cyanoacetate, 6-chlorotriazolopyridazine (5) was produced (75percent yield) when 2 was treated with diethyl ethoxymethylenemalonate.Treatment of 2 with diethyl acetylmalonate (8) gave both 6-chloro-3-methyltriazolopyridazine (10) and 5-hydroxy-3-methyl-1-(6-chloro-3-pyridazinyl)-1H-pyrazole-4-carboxylic acid ethyl ester (12).Pyrazole 12 was initially isolated as a salt of triazolopyridazine 10.
