69729-73-3Relevant academic research and scientific papers
A simple and efficient approach to quinazolinones under mild copper-catalyzed conditions
Liu, Xiaowei,Fu, Hua,Jiang, Yuyang,Zhao, Yufen
supporting information; experimental part, p. 348 - 351 (2009/04/14)
(Chemical Equation Presented) Cop some rings: A simple and highly efficient copper-catalyzed method for the synthesis of quinazolinone derivatives through the reaction of substituted 2-halobenzoic acids with amidines or guanidines under mild conditions ha
Highly efficient copper-catalyzed cascade synthesis of quinazoline and quinazolinone derivatives
Huang, Cheng,Fu, Yuan,Fu, Hua,Jiang, Yuyang,Zhao, Yufen
supporting information; experimental part, p. 6333 - 6335 (2009/04/13)
We have developed a general and highly efficient copper-catalyzed method for synthesis of quinazoline and quinazolinone derivatives, the target products were obtained in good to excellent yields via cascade reactions of amidine hydrochlorides with substituted 2-halobenzaldehydes, 2-halophenylketones, or methyl 2-halobenzoates, and the method is of simple, economical and practical advantages. The Royal Society of Chemistry 2008.
